AI Article Synopsis
- - Heterotopic ossification is the abnormal formation of bone in soft tissues (like muscles) often due to injuries, surgeries, or nerve damage, leading to symptoms like joint swelling and pain, mainly around the hips, knees, and elbows.
- - Prevention methods include drugs, radiotherapy, molecular biology interventions, and some traditional Chinese medicine practices, with drugs and radiotherapy being the most effective.
- - Treatment options range from medications and physical therapy to surgery, which is the most effective, although there is ongoing debate about the timing and techniques of surgical intervention.
Article Abstract
Heterotopic ossification is the formation of pathological bone in non-skeletal tissues (including muscles, tendons or other soft tissues), and the pathogenesis is not completely clear. It is often caused by musculoskeletal trauma, postoperative bone and joint surgery, or damage of the nervous system, the clinical manifestations are joint swelling, pain, and movement disorders, which often occur around the hips, knees, and elbows. At present, the prevention of heterotopic ossification mainly includes drugs, radiotherapy, molecular biological mechanism intervention, and Chinese medicine-related measures. Among them, drugs and radiotherapy are more effective methods to prevent heterotopic ossification. The intervention of molecular biology mechanism to prevent heterotopic ossification has become a new research direction and focus of attention inrecent years, and is basically at the experimental research stage. The treatment of heterotopic ossification includes various methods such as drugs, physical therapy, and surgery. Among them, surgery is recognized as the most effective treatment, however there are still some controversies and disagreements about the choice of operation time and surgical methods.
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| http://dx.doi.org/10.12200/j.issn.1003-0034.2020.03.021 | DOI Listing |
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