Clinical complications of biodegradable screws for ligament injuries.

Mater Sci Eng C Mater Biol Appl

Department of Orthopaedics, UConn Health, Farmington, CT, 06030, USA. Electronic address:

Published: April 2020

AI Article Synopsis

  • The anterior cruciate ligament (ACL) is essential for knee stability, and untreated injuries can cause further damage like meniscus tears and osteoarthritis.
  • Metal interference screws, used for graft fixation, have drawbacks such as mechanical mismatches and complications during post-operative imaging.
  • Biodegradable polymeric screws offer benefits but show long-term complications, emphasizing the need for better material engineering in orthopedic screw development for effective ligament repairs.

Article Abstract

Anterior cruciate ligament (ACL) plays a crucial role stabilizing the knee joint while connecting tibia to femur. Lack of proper treatment of injured ACL can lead to meniscus tear and osteoarthritis. Interference screws secure the graft tissue for superior integration of graft on host tissue during autograft fixation. Metal interference screws come with various disadvantages like mechanical load mismatch, graft laceration, secondary surgical removal and hindrance during MRI and CT post-operative scan. Though biodegradable polymeric screws provide various advantages their clinical outcomes reveal unprecedented complications for long term use of such screws. This review highlights polymer and composite screw currently available for surgical fixations and associated adverse reactions with the proposed mechanism for tunnel enlargement, effusion, osteolysis in ligament repairs. The need for suitable material engineering for development of orthopedic screws for successful rigid fixation has been highlighted in this review.

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Source
http://dx.doi.org/10.1016/j.msec.2019.110423DOI Listing

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