Human angiostrongyliasis is an important foodborne helminthic zoonosis caused by the nematodes of the genus . We describe two parasitologically confirmed cases of ocular angiostrongyliasis, presenting at a tertiary care hospital in Thailand between 2012 and 2018. Parasites were surgically recovered from patients' eyes and morphologically identified as species. DNA analysis allowed identification of . Polymerase chain reaction was used to amplify all or part of the small nuclear ribosomal subunit, the second internal transcribed spacer region, and cytochrome c oxidase subunit 1. The sequences subsequently obtained were highly similar to those of (97-100%). This is the first molecular confirmation that is a causative agent of human angiostrongyliasis in Thailand.
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http://dx.doi.org/10.4269/ajtmh.19-0701 | DOI Listing |
J Curr Ophthalmol
August 2023
Department of Ophthalmology, Faculty of Medicine, Naresuan University, Phitsanulok, Thailand.
Purpose: To report the clinical course and optical coherence tomography (OCT) findings of ocular angiostrongyliasis.
Methods: A 36-year-old female with a history of ingesting regular raw freshwater shrimp and other raw food presented with acute unilateral painless visual loss in the right eye. Her right eye's best-corrected visual acuity (BCVA) was 1 ft of the count finger.
Parasitol Res
September 2023
Department of Microbiology and Parasitology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.
Angiostrongylus cantonensis, or the rat lungworm, is the causative agent of human angiostrongyliasis associated with eosinophilic meningitis or meningoencephalitis. Additionally, this nematode can cause ocular angiostrongyliasis, though this is rare. The worm can cause permanent damage to the affected eye and sometimes even blindness.
View Article and Find Full Text PDFPathogens
June 2023
Department of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources/CINeZ, Czech University of Life Sciences Prague, 16500 Prague-Suchdol, Czech Republic.
Human angiostrongylosis is an emerging zoonosis caused by the larvae of three species of metastrongyloid nematodes of the genus with (Chen, 1935) being dominant across the world. Its obligatory heteroxenous life cycle includes rats as definitive hosts, mollusks as intermediate hosts, and amphibians and reptiles as paratenic hosts. In humans, the infection manifests as eosinophilic meningitis (AEM) or ocular form.
View Article and Find Full Text PDFPathogens
April 2023
Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI 96822, USA.
is the main causative agent for eosinophilic meningoencephalitis in humans. Larvae are rarely found in the cerebral spinal fluid (CSF). Consequently, serology and DNA detection represent important diagnostic tools.
View Article and Find Full Text PDFVet Parasitol
April 2023
Faculty of Veterinary, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90540-000, Brazil.
Livestock is an important part of many countries gross domestic product, and sanitary control impacts herd management costs. To contribute to incorporating new technologies into this economic chain, this work presents a mobile application for decision assistance to treatment against parasitic infection by Haemonchus contortus in small ruminants. Based on the Android system, the proposed software is a semi-automated computer-aided procedure to assist Famacha© pre-trained farmers in applying anthelmintic treatment.
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