Two new pyrrolizidine alkaloids, sclerwalins A and B ( and ), and one known 9-O-E-hydroxysenecioylretronecine () were first isolated from the seeds of . Their chemical structures were elucidated by extensive 1 D NMR and 2 D NMR (HSQC, HMBC, COSY, and ROESY), MS and IR spectra. Cytotoxicities of all isolates were evaluated against five human tumor cell lines (HL-60, A-549, SMMC-7721, MCF-7 and SW480).[Formula: see text].
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