AI Article Synopsis
- - The study highlights the importance of focusing on both oligomerization and oxidative cyclization in creating 5,10,15-tris(trifluoromethyl)corrole, showing that PIFA is a better oxidant for this process.
- - Using optimized conditions, researchers achieved a significant increase, yielding six times more of the pure free-base corrole and eleven times more isolated material than before.
- - The gallium(III) and manganese(III) complexes of the corrole were successfully obtained by introducing the correct metal salts before purifying the corrole.
Article Abstract
Separate focus on the oligomerization and oxidative cyclization steps required for the synthesis of 5,10,15-tris(trifluoromethyl)corrole revealed [bis(trifluoroacetoxy)iodo]benzene (PIFA) as a superior alternative oxidant. Under optimized conditions, the pure free-base corrole was obtained with a 6-fold increase in chemical yield and an 11-fold rise in isolated material per synthesis. The corresponding gallium(III) and manganese(III) complexes were isolated by adding the appropriate metal salt prior to corrole purification.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187640 | PMC |
| http://dx.doi.org/10.1021/acs.orglett.0c00879 | DOI Listing |
Publication Analysis
Top Keywords
enhanced synthetic
4
synthetic access
4
access tris-cf-substituted
4
tris-cf-substituted corroles
4
corroles separate
4
separate focus
4
focus oligomerization
4
oligomerization oxidative
4
oxidative cyclization
4
cyclization steps
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!