Three new tuberostemoamide-type alkaloids, stemtuberolines A-C (1-3), four new stenine-type alkaloids, stemtuberolines D-G (4-7), together with five known Stemona alkaloids (8-12), were isolated from the roots of Stemona tuberosa. Their structures were elucidated on the basis of comprehensive spectroscopic data analysis. Stemtuberoline C (3) exhibited significant anti-TMV activity with an inhibition rate of 60.48% at the concentration of 50 μg/mL, while that of ningnamycin, the positive control, was 52.89%.
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| http://dx.doi.org/10.1016/j.fitote.2020.104572 | DOI Listing |
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