The frequency, pattern, and predictive factors for skip LN metastasis in patients with papillary thyroid carcinoma (PTC) remain controversial. In this study, we evaluated predictive factors of skip LN metastasis in these patients. We reviewed the medical records of 68 PTC patients who underwent total thyroidectomy, central neck dissection, and lateral neck dissection at the initial operation. The relationships between skip LN metastasis and clinicopathologic factors were analyzed. After careful examination of electronic medical records of patients, 19 patients were excluded from the study. Of the remaining 49 patients, 9 (18.4%) had skip LN metastasis. Multivariate analysis showed that tumor size <1 cm was an independent risk factor for the presence of skip metastasis ( = 0.035, odds ratio: 3.78, 95% confidence interval: 1.09-13.15). The rate of positive LN was relatively higher in micro-PTC patients than PTC patients. This finding is clinically significant and should be considered in routine clinical practice.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
The prognostic implication of skip metastasis to lateral neck in patients with papillary thyroid cancer.
Quant Imaging Med Surg
December 2024
Department of Ultrasound, Chinese Academy of Medical Sciences & Peking Union Medical College Hospital, Beijing, China.
Background: Pre-operative detection of skip metastasis in papillary thyroid cancer (PTC) is significant in preventing recurrence. The study aimed to investigate the characteristics and prognosis of skip metastasis to lateral neck in PTC patients by a cross-sectional study.
Methods: Between 2013 and 2016, 494 patients who underwent thyroidectomy for PTC and positive lateral lymph node metastases (LLNM) were retrospectively identified.
Level V metastases in node positive oral squamous cell carcinoma - beyond level IIA and III.
ORL J Otorhinolaryngol Relat Spec
December 2024
Introduction Surgical management of level V in clinically node positive (cN+) oral squamous cell carcinomas (OSCC) is controversial. The objectives of the study were to identify predictors of level V metastases in cN+ OSCC. Methods This retrospective study is based on institutional data of operated cN+ OSCC between April 2018 and December 2022.
View Article and Find Full Text PDFSpatiotemporal Mapping of Lymphatic Metastases in Gastric Cancer Using Tumor-Trackable and Enzyme-Activatable Near-Infrared Fluorescent Nanoprobes.
ACS Nano
December 2024
Department of Gastrointestinal Surgery, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou 510317, China.
Sentinel lymph node biopsy holds significant importance in cancer management, yet the challenge persists in early detection and precise resection of metastasis lymph nodes (LNs) due to the absence of specific and sensitive optical probes. This study reports metastatic LN reporters (MLRs) with an activatable optical output for accurate spatiotemporal mapping of lymphatic metastases in gastric cancer. MLRs are self-assembled entities incorporating mixed amphiphiles with a lipophilic tail and a tumor-targeting ligand or a fluorescent moiety that is caged with a switch cleavable by tumor-specific β-galactosidase (β-Gal).
View Article and Find Full Text PDFBMSMM-Net: A Bone Metastasis Segmentation Framework Based on Mamba and Multiperspective Extraction.
Acad Radiol
November 2024
Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Yunnan Key Laboratory of Computer Technologies Application, Kunming, China (F.S., S.T., X.W., Y.L., L.W.). Electronic address:
Rationale And Objectives: Metastatic bone tumors significantly reduce patients' quality of life and expedite cancer spread. Traditional diagnostic methods rely on time-consuming manual annotations by radiologists, which are prone to subjectivity. Employing deep learning for rapid, precise segmentation of bone metastases can greatly improve patient outcomes and survival.
View Article and Find Full Text PDFThe Survival, Mechanisms of Failure, and Function After Total Humeral Replacement in Patients with Primary Sarcomas.
J Shoulder Elbow Surg
November 2024
Department of Orthopaedic Oncology Surgery, Beijing Jishuitan Hospital,Capital Medical University, Beijing 100035,China; National Center for Orthopedics,Beijing 100035, China; Beijing Research Institute of Traumatology and Orthopaedics, Beijing, 100035, China. Electronic address:
Background: Total humeral replacement (THR) is one of the few options for reconstruction when the humerus is extensively involved or with skip lesions. However, there are few studies focusing on the long-term outcomes of THR for primary sarcomas, and the function and endoprosthesis survival remains uncertain.
Questions/purposes: The purposes of this study were to answer the following questions: 1) What are the oncological and functional outcomes of total humeral replacement? 2) What are the overall survival and revision-free survival rates of total humeral replacement? 3) What are the failure mechanisms of total humeral replacement?
Methods: A retrospective cohort study was conducted on 34 patients (22 males, 12 females) between January 1997 and December 2021.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!