Objective: This study was performed to evaluate a new type of autologous muscle tamponade to repair dura mater that has undergone dural defects to prevent cerebrospinal fluid leakage or subcutaneous fluid accumulation.
Methods: Three hundred thirty-two patients who underwent retrosigmoid craniotomy were selected and divided into two groups: bone window craniotomy and bone flap craniotomy. Each group was further divided into two groups: artificial dura repair and autologous muscle repair. We then analysed the incidence of postoperative cerebrospinal fluid leakage or subcutaneous fluid accumulation and compared the effects of the two repair methods.
Results: For all patients, autologous muscle repair of the dura mater had a lower incidence of cerebrospinal fluid leakage than artificial dura mater repair, especially in patients with craniotomy.
Conclusions: Subdural craniotomy of the bone window is more effective than conventional methods in preventing cerebrospinal fluid leakage.
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http://dx.doi.org/10.1177/0300060520910299 | DOI Listing |
Brain Behav
December 2024
Department of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Purpose: This study aims to explore the neuroprotective effect of propofol in improving traumatic brain injury (TBI) by inhibiting ferroptosis through the modulation of the endothelial nitric oxide (NO) synthase (eNOS)/NO signaling pathway.
Methods: The GSE173975 dataset was used to analyze the differentially expressed genes between TBI and sham surgery control groups in the short and long term. A TBI model was established in 2-month-old male SPF C57BL/6 mice by impact exposure of the exposed dura mater.
J Med Case Rep
December 2024
UZ Leuven, Plastic, Reconstructive and Aesthetic Surgery, Herestraat 49, 3000, Louvain, Belgium.
Background: NeoDura (Medprin Biotech Gmbh) is an absorbable dural repair patch consisting of degradable poly-L-lactic acid and porcine gelatin that provides a hermetic closure of the dura mater (Medprin Biotech. Neodura. Dural Repair Patch [Brochure].
View Article and Find Full Text PDFPurpose: The reconstruction of dura matter is a challenging problem for neurosurgeons. A number of materials for dural reconstruction have recently been developed, but some of them have poor biocompatibility, poor mechanical properties, and adverse effects. Bovine parietal peritoneum is a promising natural material for regenerative medicine and reconstructive surgery.
View Article and Find Full Text PDFCurr Med Imaging
December 2024
Department of Vascular Neurosurgery, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez", 14267, Mexico City, Mexico.
Background: Castleman disease (CD) is a rare lymphoproliferative disorder, with intracranial involvement being exceedingly rare. Unicentric Castleman disease (UCD) is typically benign and localized, but its presentation can mimic other intracranial pathologies, complicating diagnosis.
Case Description: We reported a 52-year-old woman who presented with progressive headaches and language disturbances.
Nat Cancer
December 2024
Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
The cerebrospinal fluid (CSF) border accommodates diverse immune cells that permit peripheral cell immunosurveillance. However, the intricate interactions between CSF immune cells and infiltrating cancer cells remain poorly understood. Here we use fate mapping, longitudinal time-lapse imaging and multiomics technologies to investigate the precise origin, cellular crosstalk and molecular landscape of macrophages that contribute to leptomeningeal metastasis (LM) progression.
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