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Availability and quality assessment of Clinical Practice Guidelines on orthoplastic surgery treatment of open fractures of the lower limb using AGREE II tool: A systematic review.
J Plast Reconstr Aesthet Surg
January 2025
Department of Plastic and Reconstructive Surgery, University of Trieste, Trieste, Italy.
Introduction: Orthoplastic surgery, which combines orthopedic and plastic surgery principles, plays a crucial role in the treatment of open fractures of the lower limb. Clinical Practice Guidelines (CPGs) are valuable tools for standardizing and improving patient care.
Objective: To assess the availability and quality of international CPGs for orthoplastic treatment of open fractures of the lower limb.
induces the expression of Lgr5 and stem cell properties in gastric target cells.
Life Sci Alliance
November 2024
Institute of Molecular Cancer Research, University of Zürich, Zürich, Switzerland
infection predisposes carriers to a high risk of developing gastric cancer. The cell-of-origin of antral gastric cancer is the Lgr5 stem cell. Here, we show that infection of antrum-derived gastric organoid cells with increases the expression of the stem cell marker Lgr5 as determined by immunofluorescence microscopy, qRT-PCR, and Western blotting, both when cells are grown and infected as monolayers and when cells are exposed to in 3D structures.
View Article and Find Full Text PDFA Multi-Center Retrospective Observational Analysis of Three-Year Experience of Our Protocol for Prevention and Monitoring of Surgical Site Infections in Implant-Based Breast Reconstruction.
Cancers (Basel)
July 2024
Plastic Surgery Department, Ospedale di Cattinara, ASUGI, Strada di Fiume, 447, 34149 Trieste, Italy.
Background: With the rise in the mastectomy rate, the number of patients who choose to undergo postmastectomy reconstruction has been increasing, and implant-based procedures are the most performed methods for postmastectomy breast reconstruction. Among the possible complications, the most feared is the loss of reconstruction. It can be related to several reasons, but one of the most common is infection of the implant, which can lead to prolonged antibiotic treatment, undesired additional surgical procedures, increased incidence of capsular contracture, and unsatisfactory aesthetics results, with a huge psychological impact on patients.
View Article and Find Full Text PDFAnti-infective management of infected skin ulcers.
Infez Med
June 2024
Clinical Microbiology and Virology Unit, Great Metropolitan Hospital "Bianchi-Melacrino-Morelli", Reggio Calabria, Italy.
Article Synopsis
- * The paper highlights the importance of anti-infective therapy in managing these ulcers and discusses various clinical classifications and diagnostic traits.
- * It outlines decision-making processes for treatment, evaluation of infections, duration of antibiotics, and techniques for monitoring recovery, including outpatient treatment options.
Secondary Microsurgical Reconstruction of the Cervical Esophagus: Safer Flaps and Practical Tips in a Challenging Situation.
J Clin Med
May 2024
Plastic Surgery Department, Ospedale di Cattinara, ASUGI (Azienda Sanitaria Universitaria Giuliano Isontina), 34149 Trieste, Italy.
: Cervical esophageal reconstruction is vital to improve the quality of life in cancer surgery patients. Microsurgery is crucial in providing vascularized tissue for defect repair, particularly in secondary cases with a higher risk of failure due to larger defects and damage from previous surgery and radiotherapy. The purpose of this study was to describe the clinical characteristics of a series of patients who underwent secondary repair of esophageal defects and provide practical information for the management and treatment of such cases based on the authors' experience and the literature review.
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