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Case Report: Winkelmann hip rotationplasty as a last-resort solution.
Front Surg
January 2025
Service de Chirurgie Orthopédique et Traumatologique, Cliniques Universitaires Saint-Luc, Bruxelles, Belgique.
Background: Rotationplasty, an invasive surgery, serves as an alternative to amputation in pediatric orthopedic oncology. It is currently applied in broader cases (e.g.
View Article and Find Full Text PDFVvax001, a Therapeutic Vaccine for Patients with HPV16-positive High-grade Cervical Intraepithelial Neoplasia: a Phase II Trial.
Clin Cancer Res
January 2025
University Medical Center Groningen, Groningen, Netherlands.
Purpose: Human papillomavirus (HPV) infection is the major cause of (pre)malignant cervical lesions. We previously demonstrated that Vvax001, a replication-incompetent Semliki Forest virus (SFV) vaccine encoding HPV type 16 (HPV16) E6 and E7, induced potent anti-E6 and -E7 cytotoxic T-cell responses. Here, we investigated the clinical efficacy of Vvax001 in patients with HPV16-positive cervical intraepithelial neoplasia grade 3 (CIN3).
View Article and Find Full Text PDFSexual practices and risk behaviours towards human immunodeficiency virus (HIV) infection among Ecuadorian university students: a cross-sectional study.
Sex Transm Infect
January 2025
Colegio de Ciencias de la Salud, Universidad San Francisco de Quito USFQ, Quito, Ecuador
Objective: To describe the sexual practices and behaviour towards HIV infection among Ecuadorian university students.
Methods: This was a cross-sectional, descriptive study carried out between February 2019 and August 2020 among university students from all over the country. Students aged 18 years and older of each participating institution were contacted by an official email account and invited to fill out a survey through Google Forms.
Successful treatment of chronic migraine unresponsive to triptans with herbal medicines containing Cinnamomi Cortex: A case report.
Explore (NY)
January 2025
Suchangdang Korean Medicine Clinic, Seoul 06084, Republic of Korea.
Background: Migraine is a neurological disorder characterized by severe, unilateral, pulsating headaches with visual, olfactory, and auditory hypersensitivity, as well as autonomic symptoms. Currently, triptans are the standard treatment, but they often fail to relieve symptoms. Herbal medicines are alternative treatments to overcome these limitations.
View Article and Find Full Text PDFQM Investigation of Rare Earth Ion Interactions with First Hydration Shell Waters and Protein-Based Coordination Models.
J Phys Chem B
January 2025
Department of Biomedical Engineering, The University of Texas at Austin, Austin, Texas 78712, United States.
Conventional methods for extracting rare earth metals (REMs) from mined mineral ores are inefficient, expensive, and environmentally damaging. Recent discovery of lanmodulin (LanM), a protein that coordinates REMs with high-affinity and selectivity over competing ions, provides inspiration for new REM refinement methods. Here, we used quantum mechanical (QM) methods to investigate trivalent lanthanide cation (Ln) interactions with coordination systems representing bulk solvent water and protein binding sites.
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