Background: Little is known to what extent attitudes of ICU clinicians are influenced by new insights and recommendations to be more conservative with oxygen therapy. Our aim was to investigate whether implementation of a conservative oxygenation guideline structurally changed self-reported attitudes and actual clinical practice.
Methods: After the implementation of a conservative oxygen therapy guideline in 3 teaching hospitals in the Netherlands, ICU clinicians were surveyed regarding their attitudes toward oxygen therapy. The survey results were compared with survey results taken before the introduction of the new guideline. Arterial blood gas analysis data and ventilator settings were retrieved from all patients admitted to the participating ICUs in the studied period, and changes after implementing the guideline were assessed.
Results: In total, 180 ICU clinicians returned the survey. Compared to before implementation of a conservative oxygen guideline, more clinicians chose a preferred [Formula: see text] and an oxygen saturation measured from an arterial sample ([Formula: see text]) limit after implementation of the guideline. In general, clinicians reported a more conservative approach toward management of [Formula: see text] and less frequently increased the [Formula: see text]. In the period after the active implementation of the guideline, 5,840 subjects were admitted to the participating ICUs and 101,869 arterial blood gas analyses were retrieved. Actual practice changed with overall lower oxygenation levels (median [Formula: see text] 77.93 mm Hg, compared to 86.93 mm Hg before implementation) of arterial blood and a decrease of PEEP and [Formula: see text].
Conclusions: Implementing a conservative oxygenation guideline was an effective method that changed self-reported attitudes and actual clinical practice and improved adherence to conservative oxygenation targets in a short period of time.
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http://dx.doi.org/10.4187/respcare.07527 | DOI Listing |
Sci Rep
January 2025
Center for Animal Welfare Science, Departments of Comparative Pathobiology and Animal Science, Purdue University, West Lafayette, IN, 47907, USA.
It is well established that maternal factors can affect the abilities of offspring to cope with stressors and can influence their overall welfare states. However, maternal effects have not been extensively explored in US commercial breeding kennels (CBKs). Therefore, the objective of this study was to identify if fear and stress in dams affected puppy welfare metrics in CBKs.
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January 2025
Dep. Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, 1081, LA, The Netherlands.
The increasing use of recreational nitrous oxide ([Formula: see text]O) in the Netherlands and its link to traffic accidents highlights the need for reliable detection methods for law enforcement. This study focused on ex vivo detection of [Formula: see text]O in exhaled breath and examining its persistence in the human body. Firstly, a low-cost portable infrared based detector was selected and validated to detect [Formula: see text]O in air.
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January 2025
School of Physics, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.
The ground states of two-species condensates with spin-1 atoms have been studied analytically and numerically. All the results from the analytical approach are checked by the latter. The [Formula: see text] channel has been neglected, where λ is the coupled spin of two different atoms.
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January 2025
Helmholtz-Zentrum Berlin für Materialien und Energie, 13109, Berlin, Germany.
Incommensurate magnetic phases in chiral cubic crystals are an established source of topological spin textures such as skyrmion and hedgehog lattices, with potential applications in spintronics and information storage. We report a comprehensive small-angle neutron scattering (SANS) study on the B20-type chiral magnet Cr[Formula: see text]Mn[Formula: see text]Ge, exploring its magnetic phase diagram and confirming the stabilization of a skyrmion lattice under low magnetic fields. Our results reveal a helical ground state with a decreasing pitch from 40 to 35 nm upon cooling, and a skyrmion phase stable in applied magnetic fields of 10-30 mT, and over an unusually wide temperature range for chiral magnets of 6 K ([Formula: see text], [Formula: see text] K).
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January 2025
Yunnan Institute of Building Research Ltd, Kunming, Yunnan, 650223, China.
Due to various factors, the concrete may contain mud, a condition that can lead to a decrease in strength and changes in the ultrasonic acoustic parameters of the concrete. In order to study the effect of concrete mud content ([Formula: see text]) on ultrasonic acoustic parameters and compressive strength, this paper firstly derived the relationship equations between concrete mud content and acoustic parameters and compressive strength. Subsequently, the acoustic parameters and compressive strength were tested for concrete specimens with different mud contents cast on site.
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