AI Article Synopsis
- Six new -inositol derivatives were found in Vietnamese leaves and their chemical structures were determined using advanced analytical methods like NMR and HRESIMS.
- All compounds were tested for their ability to inhibit nitric oxide production triggered by lipopolysaccharide in RAW 264.7 macrophage cells.
- One compound showed strong inhibitory effects on NO production with an IC value of 7.1 μM.
Article Abstract
Six new -inositol derivatives (-) were isolated from the leaves of collected in Vietnam. Their chemical structures were elucidated by 1D and 2D NMR and HRESIMS analyses. All isolated compounds were evaluated for their inhibitory activity against lipopolysaccharide-induced nitric oxide (NO) production in the RAW 264.7 macrophage cell line. Compound exhibited potent inhibitory activity for NO production with an IC value of 7.1 μM.
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| http://dx.doi.org/10.1021/acs.jnatprod.9b01239 | DOI Listing |
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