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Mouse pulmonary response following solid surface composite dust inhalation.
Inhal Toxicol
January 2025
Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
: Pulmonary exposure to emissions from manipulating solid surface composite (SSC) materials has been associated with adverse health effects in humans and laboratory animals. Previous and investigations of SSC toxicity have been limited by particle delivery methods that do not fully recapitulate the workplace environment. This study sought to determine the acute SSC-induced pulmonary responses whole-body inhalation exposure.
View Article and Find Full Text PDFTherapeutic Effect of Glucose-Insulin-Potassium (GIK) Infusion Therapy in the Treatment of Acute Aluminum Phosphide Poisoning: An Institutional Study.
Cureus
December 2024
Anesthesia Department, PGY2 Anesthesia, Lady Reading Hospital, Peshawar, PAK.
Background: Acute aluminum phosphide (ALP) poisoning presents a significant global medical challenge, particularly in regions where it is commonly used as a pesticide. Despite medical advancements, mortality rates from ALP poisoning remain high. Glucose-insulin-potassium (GIK) infusion therapy has emerged as a potential treatment for ALP poisoning due to its ability to counteract its toxic effects on metabolism and heart function.
View Article and Find Full Text PDFThe potential role of N-acetylcysteine as an adjuvant therapy in acute aluminum phosphide poisoning: a randomized clinical trial.
Toxicol Res (Camb)
February 2025
Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Menoufia University, Yassen Abd Al Ghafar Street, Shibin El-Kom 6132720, Egypt.
Objective: Aluminum phosphide (AP) intoxication is a life-threatening emergency with no available effective antidote. This study evaluated the efficacy and safety of N-acetylcysteine (NAC) infusion in cases of acute AP poisoning.
Methods: This randomized, single-blinded, parallel-group, controlled, clinical trial enrolled 96 patients with acute AP poisoning.
An alternative approach to the detection of latent fingermarks using [Eu(BDC)3(HO)], a luminescent non-toxic MOF powder.
J Forensic Sci
January 2025
LIMA, Instituto de Química, Universidade de Brasília-UnB, Brasília, Brazil.
Fingermarks are important forensic evidence for identifying people. In this work, luminescent MOF [Eu(BDC)(HO)] (herein referred as EuBDC) was tested as a potential latent fingermark (LF) luminescent developer powder and its acute toxicity evaluated following OECD protocol 423. The results showed that the powder can develop groomed LF on materials such as leather, plastic, metal, glass, cardboard, and aluminum.
View Article and Find Full Text PDFArterial blood gases and serum cortisol level as predictors for mortality in acute aluminum phosphide poisoned patients: A prospective cohort study.
Toxicol Rep
June 2025
Forensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Tanta University, Egypt.
Aluminum phosphide (ALP) is an extremely toxic substance that causes significant morbidity and mortality. Early identification of patients at risk could improve their outcomes. Therefore, this study evaluated the role of serial arterial blood gases and serum cortisol levels in predicting outcomes in patients with acute ALP poisoning.
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