AI Article Synopsis
- Reactive arthritis (ReA) is characterized by a classic triad of symptoms: arthritis, conjunctivitis, and urethritis, often triggered by infections or, in rare cases, by intravesical Bacillus Calmette-Guérin (iBCG) therapy for bladder cancer.
- A reported case shows a patient with carcinoma in situ of the bladder who developed ReA after iBCG treatment, but their symptoms completely resolved after corticosteroid therapy.
- It's important to differentiate ReA from other types of arthritis, such as septic or microcrystalline arthritis, especially in patients receiving iBCG therapy.
Article Abstract
Unlabelled: Reactive arthritis (ReA) with the classic triad of arthritis, conjunctivitis and urethritis, previously termed Reiter's syndrome, is a systemic illness, usually induced by genitourinary or gastrointestinal infections. However, it can be a rare complication of intravesical Bacillus Calmette-Guérin instillation (iBCG), a therapy prepared from attenuated strains of , a common and effective treatment for carcinoma in situ of the bladder (CisB). We report a case of a patient with CisB who developed ReA after iBCG. The symptoms resolved completely with corticosteroids. iBCG was stopped with no recurrence of carcinoma within 2 years.
Learning Points: ReA is an aseptic arthritis, usually triggered by genitourinary or gastrointestinal infections, generally in individuals positive for HLA-B27.Septic arthritis and microcrystalline arthritis can mimic ReA and they must be ruled out with arthrocentesis.ReA may be considered as a complication in patients under iBCG.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083183 | PMC |
| http://dx.doi.org/10.12890/2020_001448 | DOI Listing |
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