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| http://dx.doi.org/10.1007/s13193-019-00993-8 | DOI Listing |
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Outcomes of patients with intermediate-risk neuroblastoma presenting with motor deficits relating to intraspinal tumor extension: A report from the Children's Oncology Group study ANBL0531.
Pediatr Blood Cancer
January 2025
Department of Pediatrics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Article Synopsis
- Tumor invasion of the spinal canal occurs in about 15% of newly diagnosed neuroblastoma patients, prompting a need for effective treatment strategies that optimize survival while minimizing long-term effects.
- A study of 92 intermediate-risk neuroblastoma patients with intraspinal tumors revealed that nearly half were symptomatic at diagnosis, but most of them experienced complete resolution of symptoms following treatment, regardless of the initial severity or duration of their deficits.
- The findings suggest that while prompt diagnosis and chemotherapy are crucial, surgical options like laminectomy may not significantly improve motor symptoms, indicating that surgery should be reserved for cases with rapid worsening neurologic conditions.
Primary spinal epidural abscess: magnetic resonance imaging characteristics and diagnosis.
BMC Med Imaging
October 2024
Department of Radiology, the Affiliated hospital of Qingdao Univertsity, 16.Jiangsu Road, Qingdao, Shandong Province, China.
Rationale And Objective: To investigate the MR characteristics of phlegmonous stage and abscess stage primary spinal epidural abscess.
Materials And Methods: This study retrospectively analyzed the clinical and imaging characteristics of 27 cases of pathologically confirmed primary spinal epidural abscess. Predisposing conditions of all patients were collected.
Combined Intrathoracic and Intraspinal Approach to a Neurogenic Dumbbell Tumour.
Cureus
September 2024
Cardiothoracic Surgery, Faculty of Medicine, The National University of Malaysia, Kuala Lumpur, MYS.
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- * A case study involving a 53-year-old woman highlighted a successful surgical strategy that combined laminectomy with video-assisted thoracoscopic surgery (VATS) to resect the tumour, initially discovered as a mediastinal mass on a chest X-ray.
- * Post-surgery complications included cerebrospinal fluid leakage, necessitating a second operation, but ultimately the patient recovered well, showcasing the need for a tailored, multidisciplinary approach in treating such tumours.
Posttraumatic Cutaneous Meningioma with a "Meningiolipoma" Pattern Presenting as a Nasal Bridge Mass.
Diagnostics (Basel)
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Department of Pathology and Laboratory Medicine, University of California, Irvine, CA 92697, USA.
Meningiomas are tumors originating from arachnoid meningothelial cells. Occasionally, meningiomas are identified outside the central nervous system, and are referred to as extracranial meningiomas (EMs). The vast majority of EMs are an extension from an intracranial or intraspinal tumor.
View Article and Find Full Text PDFTracking changes in image-defined risk factors during neoadjuvant chemotherapy and their predictive value for surgical outcomes based on the International Neuroblastoma Surgical Report Form.
Pediatr Blood Cancer
October 2024
Department of General Surgery, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Background: The capacity of presurgical image-defined risk factors (IDRFs) to predict secondary surgical outcomes in patients with neuroblastoma is controversial.
Methods: The International Neuroblastoma Surgical Report Form (INSRF) was employed to retrospectively collect the clinical data of 53 patients diagnosed with neuroblastoma at our hospital from April 2014 to April 2020. IDRFs were identified at the time of diagnosis and reassessed during the course of neoadjuvant chemotherapy.
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