TH17 responses in cytokine storm of COVID-19: An emerging target of JAK2 inhibitor Fedratinib.

J Microbiol Immunol Infect

Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM, 87131, USA. Electronic address:

Published: June 2020

COVID-19 emerges as a pandemic disease with high mortality. Development of effective prevention and treatment is an urgent need. We reviewed TH17 responses in patients with SARS-CoV-2 and proposed an FDA approved JAK2 inhibitor Fedratinib for reducing mortality of patients with TH17 type immune profiles.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156211PMC
http://dx.doi.org/10.1016/j.jmii.2020.03.005DOI Listing

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