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The association of previous and current non-chronic low back pain with daily physical activity in middle- and older-aged adults.
BMC Public Health
January 2025
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Background: Low back pain (LBP) is a leading cause of years lived with disability. However, the association of non-chronic LBP with levels of daily physical activity (PA) remains poorly explored. This study investigated the association between previous and current non-chronic LBP with daily PA and compliance with PA recommendations in middle and older-aged adults.
View Article and Find Full Text PDFChronic kidney disease.
Nat Rev Dis Primers
January 2025
Division of Nephrology, Department of Medicine IV, Hospital of the Ludwig-Maximilians University, Munich, Germany.
Chronic kidney disease (CKD) is defined by persistent abnormalities of kidney function or structure that have consequences for the health. A progressive decline of excretory kidney function has effects on body homeostasis. CKD is tightly associated with accelerated cardiovascular disease and severe infections, and with premature death.
View Article and Find Full Text PDFIdentification and Screening of Trace and Multityped Solvents Using Transpiration-Driven Electrokinetic Generation Principle.
Nano Lett
January 2025
School of Physical Science and Technology, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai 201210, China.
Transpiration-driven electrokinetic power generators (TEPGs) hold promising potential for intelligent chemical sensing applications, enabling the efficient identification and screening of organic solvents. Here, we report a novel TEPG-based chemical sensor using MoS-doped cellulose filter paper for efficient detection of poplar solvents like water, alcohols, and methanol. TEPGs operate by leveraging capillary-driven transpiration to induce solvent flow through porous materials, leading to ion migration and the formation of electrical double layers (EDLs) at the solid-liquid interfaces.
View Article and Find Full Text PDFIsoform-level expression of the constitutive androstane receptor (CAR or NR1I3) transcription factor better predicts the mRNA expression of the cytochrome P450s in human liver samples.
Drug Metab Dispos
January 2025
Department of Pharmacotherapy and Translational Research, College of Pharmacy, Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida. Electronic address:
Many factors cause interperson variability in the activity and expression of the cytochrome P450 (CYP) drug-metabolizing enzymes in the liver, leading to variable drug exposure and treatment outcomes. Several liver-enriched transcription factors are associated with CYP expression, with estrogen receptor α (ESR1) and constitutive androstane receptor (CAR or NR1I3) being the 2 top factors. ESR1 and NR1I3 undergo extensive alternative splicing that results in numerous splice isoforms, but how these splice isoforms associate with CYP expression is unknown.
View Article and Find Full Text PDFDeterminants of infants and young children feeding practices among mothers living in Saudi Arabia: a cross-sectional study.
BMC Public Health
January 2025
Department of Clinical Nutrition, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, P.O Box 1982, Dammam, Saudi Arabia.
Background: The WHO sets evidence-based guidelines for infant feeding. Adhering to the WHO guidelines ensures that infants receive the proper nutrition and thus is associated with healthy growth and development.
Aim: To describe breastfeeding and complementary feeding practices (CFPs) for infants and young children and identify determinants of appropriate feeding practices.
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