Background: Bamboo rats are widely farmed in southern China for meat, but their potential in transmitting pathogens to humans and other farm animals remains unclear.
Methods: To understand the transmission of Cryptosporidium spp. in these animals, 709 fecal samples were collected in this study from Chinese bamboo rats (Rhizomys sinensis) on nine farms in Jiangxi, Guangxi and Hainan provinces, China. They were analyzed for Cryptosporidium spp. using PCR and sequence analyses of the small subunit rRNA gene. Cryptosporidium parvum, C. parvum-like and C. ubiquitum-like genotypes identified were subtyped by sequence analysis of the 60 kDa glycoprotein (gp60) gene.
Results: Altogether, Cryptosporidium spp. were detected in 209 (29.5%) samples. The detection rate in samples from animals under two months of age (70.0%,105/150) was significantly higher than in samples from animals above 2 months (18.6%, 104/559; χ = 150.27, df = 1, P < 0.0001). Four Cryptosporidium species/genotypes were identified: C. parvum (n = 78); C. occultus (n = 1); a new genotype that is genetically related to C. ubiquitum (n = 85); and another new genotype that is genetically related to C. parvum (n = 44). Among them, C. parvum (27,610 ± 71,911 oocysts/gram of feces) and the C. parvum-like genotype (38,679 ± 82,811 oocysts/gram of feces) had higher oocyst shedding intensity than the C. ubiquitum-like genotype (2470 ± 7017 oocysts/gram of feces) and the C. occultus (1012 oocysts/gram of feces). The C. parvum identified belonged to three subtypes in two rare subtype families, including IIpA9 (n = 43), IIpA6 (n = 6) and IIoA15G1 (n = 9), while the C. parvum-like and C. ubiquitum-like genotypes generated very divergent gp60 sequences.
Conclusions: Results of the present study suggest that bamboo rats on the study farms were infected with diverse Cryptosporidium species and divergent C. parvum subtypes, which probably had originated from their native habitats. As similar C. parvum subtypes have been recently detected in humans and farmed macaques, attentions should be paid to the potential role of these new farm animals in the transmission of zoonotic pathogens.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092434 | PMC |
| http://dx.doi.org/10.1186/s13071-020-04021-5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Multi-functional Gleditsia sinensis galactomannan-based hydrogel with highly stretchable, adhesive, and antibacterial properties as wound dressing for accelerating wound healing.
Int J Biol Macromol
December 2024
Department of Chemistry and Chemical Engineering, Beijing Forestry University, MOE Engineering Research Center of Forestry Biomass Materials and Bioenergy, Beijing 100083, China. Electronic address:
Design and development of a multifunctional wound dressing with self-healing, adhesive, and antibacterial properties to attain optimal wound closure efficiency are highly desirable in clinical applications. Nevertheless, conventional hydrogels face significant barriers in their mechanical strength, adhesive performance, and antibacterial properties. Herein, a tough hydrogel based on aldehyde-grafted galactomannan was synthesized through radical copolymerization and Schiff base reaction, incorporating hyaluronic acid, acrylamide, and the zwitterionic monomer to create a multi-crosslinked structure.
View Article and Find Full Text PDFDietary bamboo charcoal powder ameliorates high-fat diet-induced hyperlipidemia by enhancing fecal lipid excretions in Sprague-Dawley rats.
Front Nutr
October 2024
West China School of Public Health, Sichuan University, Chengdu, Sichuan, China.
Introduction: Bamboo charcoal powder (BCP) is increasingly used as a food colorant. This study aims to evaluate the effects of BCP consumption on improving high-fat diet-induced hyperlipidemia.
Methods: Fifty male SD rats were randomly assigned into five groups, with 10 rats in each group: the control group was fed a low-fat diet (LFD); the model control group was fed a high-fat diet (HFD); the low-BCP dose group was fed a HFD and given 2.
Bold rats (Niviventer confucianus) are more effective in seed dispersal: evidence both under enclosure conditions and in the field.
Integr Zool
September 2024
Institute of Evolution and Ecology, School of Life Sciences, Central China Normal University, Wuhan, China.
Rodents are important seed dispersers of plants because they move seeds far away from the parent trees and hoard seeds in the soil, benefiting seed dispersal and regeneration. Traits of plant seeds and animals are associated with rodent-mediated seed dispersal, but animal personality, the consistent individual behavioral differences in time and environments, has not been fully considered. Here, we first measured the personality of 26 Niviventer confucianus in the laboratory, and 10 individuals in the field of one population, and then tested their behavior of seed consumption and hoarding both in semi-natural enclosures and the field.
View Article and Find Full Text PDFGenetic tracing of market wildlife and viruses at the epicenter of the COVID-19 pandemic.
Cell
September 2024
Institut d'Écologie et des Sciences de l'Environnement (IEES-Paris, UMR 7618), CNRS, Sorbonne Université, UPEC, IRD, INRAE, Paris, France. Electronic address:
Article Synopsis
- Zoonotic viruses, like SARS-CoV-2, can spill over from animals to humans, often linked to animal trade, with COVID-19 traced back to the Huanan Seafood Wholesale Market.
- Analysis of environmental samples from the market in early 2020 shows high genetic diversity of SARS-CoV-2, especially near a wildlife stall that had a variety of wildlife DNA, including potential intermediate hosts.
- The research combines genomic techniques to identify specific animal species and suggest which ones should be prioritized for further research on their role in transmitting the virus.
The hypoglycemic effect of enzymatic modified dietary fiber from bamboo shoot on type 2 diabetes rats.
J Food Sci
September 2024
State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, Jiangxi, China.
Bamboo shoot is a healthy food rich in dietary fiber (DF). However, its highly insoluble DF and fibrous texture limit its application in industrially processed foods. To achieve industrial processing of bamboo shoot, cellulase was used to improve the physical characteristics of bamboo shoot DF in this study.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!