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Acute ischaemic stroke in meningoencephalitis. | LitMetric

AI Article Synopsis

  • The text discusses an 80-year-old male patient with Crohn's disease who developed meningoencephalitis while on immunosuppressive treatment and experienced stroke-like symptoms during recovery.
  • Despite initial indications that these symptoms were infection-related, MRI scans revealed an acute ischemic event instead, highlighting the complexity of diagnosing conditions in immunosuppressed patients.
  • The case emphasizes the importance of using appropriate imaging techniques, like MRI, to distinguish between ischemic events and infection-related symptoms, particularly in patients affected by Listeria.

Article Abstract

is the third most frequent cause of bacterial meningitis and has a predilection for elderly patients and the immunosuppressed. A small number of patients with meningoencephalitis have previously been reported to experience stroke-like symptoms that were attributed to microabscess formation and the mass effect of collections of infection in the brain. These infections led to temporary neurological deficits that resolved with antimicrobial treatment, rather than to true strokes with permanent neurological deficits. This report discusses the case of an 80- year-old male, who was immunosuppressed with mesalazine for the treatment of Crohn's disease, and who went on to develop meningoencephalitis. 1 week into his admission, for antibiotic therapy, the patient began to experience new onset right upper limb weakness, nystagmus and past pointing. These symptoms were initially thought to be a complication of the infection. However, subsequent diffusion-weighted MRI revealed that the patient had more likely suffered an acute ischaemic event and a contrast-enhanced MRI performed later could not detect any abscess or large infective focus in a region that could explain the symptoms. This case report highlights the fact that ischaemic and infective pathologists may coexist in immunosuppressed Listeria patients and that clinical signs and symptoms should guide the use of appropriate imaging modalities such as MRI to clarify differentials so that ischaemia is not mistaken for the more common stroke mimic caused by infection in these patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068084PMC
http://dx.doi.org/10.1259/bjrcr.20190068DOI Listing

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