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Elderly Asian Patients Have Lower Revascularisation Rates and Poorer Outcomes for ST-Elevation Myocardial Infarction Compared to Younger Patients. | LitMetric

AI Article Synopsis

  • The study investigates the outcomes of elderly Asian patients with ST-elevation myocardial infarction (STEMI) compared to younger patients, using data from a national registry in Singapore between 2007 and 2012.
  • It found that elderly patients (≥80 years) represent 9.7% of the STEMI population and suffer from more cardiovascular risk factors and lower rates of intervention compared to younger age groups.
  • The elderly patients experienced significantly higher 1-year mortality rates (60.6%) than middle-aged to old (18.3%) and young patients (4.1%), highlighting poorer overall outcomes potentially linked to age and comorbidities.

Article Abstract

Introduction: There is limited information on elderly patients presenting with ST- elevation myocardial infarction (STEMI). This study aimed to study the outcomes of elderly Asian patients with STEMI compared to younger patients.

Materials And Methods: The study utilised data from 2007 to 2012 from the Singapore Myocardial Infarction Registry, a mandatory national population-based registry. Elderly patients were defined as ≥80 years of age, middle-aged to old (MAO) patients were defined as 45-80 years of age and young patients were defined as ≤45 years of age. The primary outcome of the study was 1-year mortality and secondary outcomes included in-hospital complications and mortality.

Results: There were 12,409 STEMI patients with 1207 (9.7%) elderly patients, 10,093 (81.3%) MAO patients and 1109 (8.9%) young patients. Elderly patients had more cardiovascular risk factors and lower rates of total percutaneous coronary intervention (26.0% vs 72.4% vs 85.5%, respectively; <0.0001) compared to MAO and young patients. They had higher 1-year mortality (60.6% vs 18.3% vs 4.1%, respectively; <0.0001) when compared to MAO and young patients.

Conclusion: Elderly patients with STEMI have poorer outcomes than MAO and young patients. This is potentially attributable to a myriad of factors including age, higher burden of comorbidities and a lesser likelihood of receiving revascularisation and guideline-recommended medical therapy.

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