Objective: To investigate the effects of a heat and moisture exchanger (HME) on the temperature and humidity of inhaled gas in isoflurane-anesthetized dogs.
Study Design: Prospective, interventional study.
Animals: A total of four experimental dogs and four client-owned dogs weighing 13.9 ± 7.4 kg (mean ± standard deviation).
Methods: The four experimental dogs were anesthetized on two occasions with and without an intact HME at least 1 week apart. The four client-owned dogs were anesthetized once only for a surgical procedure and assigned to the HME group or no-HME group in alternate order, resulting in six dogs for each group. All dogs were premedicated, anesthetized with propofol and intubated. The HME was connected to the endotracheal tube. Anesthesia was maintained with isoflurane. A digital thermo-hygrometer was placed between the endotracheal tube and HME. The temperature and relative humidity of the inhaled gas were measured every 5 minutes for 60 minutes and the absolute humidity was calculated at each time point.
Results: The temperature and absolute humidity of the inhaled gas was significantly higher at 5-60 minutes after intubation in the HME group than in the no-HME group. Absolute humidity was maintained above 29 mg HO L in the HME group. No significant time-dependent effects on temperature, relative humidity or absolute humidity of the inhaled gas were observed.
Conclusions And Clinical Relevance: The temperature and absolute humidity of the inhaled gas were higher when an HME was used during isoflurane anesthesia in dogs. The use of an HME may reduce the risk of dehydration and dysfunction of the airway mucosal epithelium.
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http://dx.doi.org/10.1016/j.vaa.2020.02.003 | DOI Listing |
Introduction: Mite allergy is the most common inhalant allergen sensitivity. In addition to house dust mites, which are indoor allergens, well-known storage mites also exist.
Methods: This study examines the frequency of storage mite sensitivity in children with allergic diseases, the rate of cross-sensitization with other mite species, and the relationship between mite sensitivities and various factors such as the type of region where patients reside and meteorological data from their locations.
ACS Sens
January 2025
School of Electrical and Electronic Engineering, Yonsei University, Seoul 03722, Republic of Korea.
Bioelectronic face masks can easily collect biomarkers in saliva, in which free cortisol is abundant. However, conventional bioelectronic face masks involve significant challenges in terms of permeability and inhalation due to their nonpermeable film-type structure. Herein, we introduce a flexible and permeable nanomesh-based wearable biosensor designed for bioelectronic face masks that monitor cortisol levels.
View Article and Find Full Text PDFJ Phys Chem A
January 2025
School of Chemistry, University of Bristol, Bristol BS8 1TS, U.K.
In both nature and industry, aerosol droplets contain complex mixtures of solutes, which in many cases include multiple inorganic components. Understanding the drying kinetics of these droplets and the impact on resultant particle morphology is essential for a variety of applications including improving inhalable drugs, mitigating disease transmission, and developing more accurate climate models. However, the previous literature has only focused on the relationship between drying kinetics and particle morphology for aerosol droplets containing a single nonvolatile component.
View Article and Find Full Text PDFSci Rep
December 2024
Division of Pulmonary and Critical Care, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095-1690, USA.
Electronic cigarettes (e-cigs) fundamentally differ from tobacco cigarettes in their generation of liquid-based aerosols. Investigating how e-cig aerosols behave when inhaled into the dynamic environment of the lung is important for understanding vaping-related exposure and toxicity. A ventilated artificial lung model was developed to replicate the ventilatory and environmental features of the human lung and study their impact on the characteristics of inhaled e-cig aerosols from simulated vaping scenarios.
View Article and Find Full Text PDFCureus
November 2024
Department of Pulmonary Medicine, King's College Hospital, Dubai, ARE.
Middle Eastern countries, such as the United Arab Emirates and Oman, are affected by frequent dust storms and extreme hot climatic conditions, which can exacerbate respiratory conditions. These environmental factors are particularly injurious to asthmatic patients, as they can aggravate small airway disease (SAD), leading to increased morbidity and healthcare challenges. The evaluation of maximal mid-expiratory flow (MEF-25) as a diagnostic and therapeutic tool for early-stage small airway dysfunction is of significant clinical importance, particularly in hot and arid metropolitan environments where dusty conditions exacerbate pulmonary issues.
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