We aimed to review current literature on the discard rate of donor hearts offered to pediatric recipients and assess geographical differences. Consequences and ways to reduce the discard rate are discussed. A systemic review on published literature on pediatric transplantation published in English since 2010 was undertaken. Additionally, a survey was sent to international OPOs with the goal of incorporating responses from around the world providing a more global picture. Based on the literature review and survey, there is a remarkably wide range of discard and/or refusal for pediatric hearts offered for transplant, ranging between 18% and 57% with great geographic variation. The data suggest that that the overall refusal rate may have decreased over the last decade. Reasons for organ discard were difficult to identify from the available data. Although the refusal rate of pediatric donor hearts seems to be lower compared to that reported in adults, it is still as high as 57% with geographic variation.
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http://dx.doi.org/10.1111/petr.13674 | DOI Listing |
World J Surg Oncol
December 2024
Department of Gastroenterological Surgery, Osaka General Medical Center, 3-1-56 Mandaihigashi, Sumiyoshi-Ku, Osaka, 558-8558, Japan.
Background: The survival benefit of adjuvant chemotherapy after curative hepatectomy for colorectal cancer (CRC) liver metastases remains controversial. This retrospective study aimed to evaluate the efficacy of adjuvant chemotherapy in improving recurrence-free survival (RFS) and overall survival (OS) in patients who underwent curative hepatectomy for CRC liver metastases at a tertiary medical center.
Methods: We retrospectively analyzed clinicopathological factors in 89 patients (surgery alone, n = 63; adjuvant chemotherapy, n = 26) who underwent curative hepatectomy for CRC liver metastases from January 2010 to December 2022.
Int J Radiat Oncol Biol Phys
December 2024
Department of Radiation Oncology, St. Luke's International Hospital, St. Luke's International University, Chuo-ku, (Tokyo), Japan.
Aim: To report final results of a prospective study of stereotactic body radiotherapy (SBRT) in patients with previously untreated solitary primary hepatocellular carcinoma (HCC).
Methods: This prospective, single-arm, multicenter phase II trial recruited patients with HCC who were unsuitable for, or refused, surgery and radiofrequency ablation, with 3-year overall survival (OS) rates as the primary endpoint and survival outcomes and adverse events as secondary endpoints. The prescribed SBRT dose was 40 Gy in five fractions.
J Environ Manage
December 2024
College of Materials and Environmental Engineering, Hangzhou Dianzi University, Hangzhou, 310018, China; School of Automation, The Belt and Road Information Research Institute, Hangzhou Dianzi University, Hangzhou, 310018, China. Electronic address:
In this study, a combined system of anaerobic-oxic-anoxic-oxic, coagulation and adsorption (AOAOCA) was used to treat the real waste transfer station (WTS) wastewater. The effects of hydraulic retention time (HRT), sludge reflux ratio (SRR), mixed liquid reflux ratio (MLRR), coagulant and zeolite on the contaminants removal efficiency were investigated. When the AOAOCA system was operated at the optimal conditions (HRT of 8 d, SRR of 70%, MLRR of 200%, PAFC as coagulant with dosage of 750 ppm and 1-3 mm zeolite with filling rate of 60%), the effluent COD, NH-N and TP could reach 82.
View Article and Find Full Text PDFArq Bras Cardiol
November 2024
Department of Research, U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC), Civil Hospital Campus, Gujarat - Índia.
Background: The optimal treatment for ischemic mitral regurgitation (IMR) in patients of non-ST elevation myocardial infarction (NSTEMI) is a debated topic.
Objective: To evaluate the long term outcome on patients with NSTEMI and IMR, particularly emphasizing the comparison of treatments in those with moderate to severe MR.
Methods: We enrolled patients with NSTEMI and classified non/trivial to mild regurgitation as insignificant IMR and moderate to severe regurgitation as significant IMR.
J Health Popul Nutr
December 2024
Department of Medicine, School of Health Science, Madda Walabu University, Goba, Ethiopia.
Background: An estimated 40% of the world's population lives in malaria-prone areas, there are 300-500 million malaria episodes worldwide, and at least one million malaria fatalities occur each year which makes malaria is a major public health concern [1]. In sub-Saharan Africa, malaria claims the lives of about 90% of all people worldwide. Today, there is a growing interest in using ITNs as one of the leading strategies for the prevention and control of malaria.
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