We aimed to replicate a recent study that found a high frequency of the GBA p.K198E mutant in Colombian patients with PD. We identified the p.K198E substitution at a lower frequency in our cohort of Colombians with PD (2.1%), and this was not significantly different than controls (1.7%, P = 0.86) emphasizing the need for larger genetic studies in Latin America.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528207 | PMC |
| http://dx.doi.org/10.1016/j.parkreldis.2020.03.008 | DOI Listing |
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