Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Purpose: To investigate the changes in corneal backward scattering using Scheimpflug tomography (densitometry) 6 months after intrastromal corneal ring segments (Keraring) implant for keratoconus and to correlate with clinical results.
Methods: Along with standard ophthalmic examination, Scheimpflug tomography using Pentacam HR was performed to document corneal densitometry and corneal shape. A densitometry map was displayed using grayscale units (GSUs) ranging from 0 to 100 (minimum to maximum light scattering) in 4 concentric annuluses: central 2-, 2- to 6-, 6- to 10-, 10- to 12-, and total 12-mm corneal diameter and at 3 different depths: anterior 120 μm, posterior 60 μm, middle (varying accordingly to the total thickness), and total thickness.
Results: The changes in mean corneal densitometry values for anterior, central, and posterior layers were 3.82 ± 3.13, 2.70 ± 1.78, and 1.68 ± 1.52 GSU, respectively, and for annuluses of 0 to 2, 2 to 6, 6 to 10, and 10 to 12 mm were 2.96 ± 2.60, 4.53 ± 2.28, 2.09 ± 1.74, and 0.45 ± 3.93 GSU, respectively. The mean values increased for all corneal layers (P < 0.05), except in the peripheral 10- to 12-mm annulus (P> 0.05). The highest increase was in the annulus 2 to 6 mm of the anterior layer (5.72 ± 3.70 GSU). Changes in the mean densitometry showed a significant correlation with the mean of average keratometry changes only for the front corneal surface and changes in the Q-values for both corneal surfaces in the 2- to 6-mm annulus for all layers.
Conclusions: Significant increase in the corneal densitometry mainly in the anterior 2- to 6-mm annulus of the cornea is associated with the position of the ring segment implant. More studies are needed to elucidate the relevance of such findings.
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Source |
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http://dx.doi.org/10.1097/ICO.0000000000002307 | DOI Listing |
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