A water-soluble host molecule can bind tetrahydrocannabinol (Δ-THC) and its metabolites in aqueous solution. By pairing this recognition event in a sensing array with fluorescent reporters and varying external mediators, pattern recognition-based detection is possible, which allows selective discrimination of the THC metabolites. The selective sensing can be performed in aqueous solution with micromolar sensitivity, as well as in biofluids such as urine and saliva. Metabolites as similar as Δ- and Δ-THC, differing only in the position of a double bond, can be distinguished.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d0cc01489c | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Leveraging U-Net and selective feature extraction for land cover classification using remote sensing imagery.
Sci Rep
January 2025
Computer Vision Center, Universitat Autònoma de Barcelona, Barcelona, 08193, Spain.
In this study, we explore an enhancement to the U-Net architecture by integrating SK-ResNeXt as the encoder for Land Cover Classification (LCC) tasks using Multispectral Imaging (MSI). SK-ResNeXt introduces cardinality and adaptive kernel sizes, allowing U-Net to better capture multi-scale features and adjust more effectively to variations in spatial resolution, thereby enhancing the model's ability to segment complex land cover types. We evaluate this approach using the Five-Billion-Pixels dataset, composed of 150 large-scale RGB-NIR images and over 5 billion labeled pixels across 24 categories.
View Article and Find Full Text PDFHotspots of genetic change in Yersinia pestis.
Nat Commun
January 2025
State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing, China.
The relative contributions of mutation rate variation, selection, and recombination in shaping genomic variation in bacterial populations remain poorly understood. Here we analyze 3318 Yersinia pestis genomes, spanning nearly a century and including 2336 newly sequenced strains, to shed light on the patterns of genetic diversity and variation distribution at the population level. We identify 45 genomic regions ("hot regions", HRs) that, although comprising a minor fraction of the genome, are hotbeds of genetic variation.
View Article and Find Full Text PDFSINE retrotransposons import polyadenylation signals to 3'UTRs in dog (Canis familiaris).
Mob DNA
January 2025
Department of Biology, La Sierra University, Riverside, CA, USA.
Background: Messenger RNA 3' untranslated regions (3'UTRs) control many aspects of gene expression and determine where the transcript will terminate. The polyadenylation signal (PAS) AAUAAA (AATAAA in DNA) is a key regulator of transcript termination and this hexamer, or a similar sequence, is very frequently found within 30 bp of 3'UTR ends. Short interspersed element (SINE) retrotransposons are found throughout genomes in high copy numbers.
View Article and Find Full Text PDFThymine-capped mesoporous silica nanoparticles as ion-responsive release system: A paper-based colorimetric sensing platform for rapid and selective mercuric identification.
Biosens Bioelectron
December 2024
School of Pharmacy, Xi'an Medical University, Xi'an, 710021, China; Institute of Medicine, Xi'an Medical University, Xi'an, 710021, China. Electronic address:
In this study, a convenient method was proposed for the synthesis of thymine-capped mesoporous silica nanoparticles (MSN) using strong hydrogen bonding in non-protonic solvent. Furthermore, application of the functionalized MSN for the recognition of mercuric ion (Hg) based on a paper-based platform with smartphone-assisted colorimetric detection was developed. The synthesized materials were characterized by techniques including X-ray diffraction (XRD), fourier-transform infrared spectroscopy (FTIR), N adsorption-desorption, particle size analysis, transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and thermogravimetric analysis (TGA).
View Article and Find Full Text PDFRoadmap for Borophene Gas Sensors.
ACS Sens
January 2025
Chimie des Interactions Plasma Surface group, Chemistry Department, Université de Mons, 7000 Mons, Belgium.
Borophene, a two-dimensional allotrope of boron, has emerged as a promising material for gas sensing because of its exceptional electronic properties and high surface reactivity. This review comprehensively overviews borophene synthesis methods, properties, and sensing applications. However, it is crucial to acknowledge the substantial gap between the abundance of theoretical literature and the limited experimental studies.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!