Background: Three clusters of coronavirus disease 2019 (COVID-19) linked to a tour group from China, a company conference, and a church were identified in Singapore in February, 2020.
Methods: We gathered epidemiological and clinical data from individuals with confirmed COVID-19, via interviews and inpatient medical records, and we did field investigations to assess interactions and possible modes of transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Open source reports were obtained for overseas cases. We reported the median (IQR) incubation period of SARS-CoV-2.
Findings: As of Feb 15, 2020, 36 cases of COVID-19 were linked epidemiologically to the first three clusters of circumscribed local transmission in Singapore. 425 close contacts were quarantined. Direct or prolonged close contact was reported among affected individuals, although indirect transmission (eg, via fomites and shared food) could not be excluded. The median incubation period of SARS-CoV-2 was 4 days (IQR 3-6). The serial interval between transmission pairs ranged between 3 days and 8 days.
Interpretation: SARS-CoV-2 is transmissible in community settings, and local clusters of COVID-19 are expected in countries with high travel volume from China before the lockdown of Wuhan and institution of travel restrictions. Enhanced surveillance and contact tracing is essential to minimise the risk of widespread transmission in the community.
Funding: None.
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http://dx.doi.org/10.1016/S0140-6736(20)30528-6 | DOI Listing |
Cell Mol Biol (Noisy-le-grand)
January 2025
Dept. of Genetics and Plant Breeding, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, Bangladesh.
Rice salt tolerance is highly anticipated to meet global demand in response to decreasing farmland and soil salinization. Therefore, dissecting the genetic loci controlling salt tolerance in rice for improving productivity is of utmost importance. Here, we evaluated six salt-tolerance-related traits of a biparental mapping population comprising 280 F2 rice individuals (Oryza sativa L.
View Article and Find Full Text PDFXi Bao Yu Fen Zi Mian Yi Xue Za Zhi
January 2025
Business Department, Hanzhong Central Blood Station, Hanzhong 723000, China. *Corresponding authors, E-mail:
Objective This study aims to investigate and analyze the distribution of MN blood type among ethnic minorities in China. Methods Through a systematic retrieval of the 981 literature related to MN blood group distribution, 120 literature, meeting the criteria of this study, with complete data were selected. The literature covers 49 ethnic minorities.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Physics, Faculty of Science, Fasa University, Fasa, 74616-86131, Iran.
In this work, we explored the role of a single electron in the energy of neutral and charged clusters of using data visualization and statistical techniques as a new insight. Initially, we studied the effects of one electron, time, and temperature on energy using multiple linear regression analysis with dummy variables, and the results demonstrated that all three predictors significantly affected the energy. Time had a positive impact (direct ratio effect) on the energy of , and and a negative impact (inverse ratio effect) on the energy of while temperature had a positive effect on the energy of all three sodium clusters.
View Article and Find Full Text PDFTransl Psychiatry
January 2025
German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Inflammation is a probable biological pathway underlying the relationship between diabetes and depression, but data on differences between diabetes types and symptom clusters of depression are scarce. Therefore, this cross-sectional study aimed to compare associations of a multimarker panel of biomarkers of inflammation with depressive symptoms and its symptom clusters between people with type 1 diabetes (T1D) and type 2 diabetes (T2D). This cross-sectional study combined data from five studies including 1260 participants (n = 706 T1D, n = 454 T2D).
View Article and Find Full Text PDFSci Rep
January 2025
Jiangxi Tellhow Power Technology Co., Ltd, Nanchang, 330031, China.
This paper presents a surrogate-assisted global and distributed local collaborative optimization (SGDLCO) algorithm for expensive constrained optimization problems where two surrogate optimization phases are executed collaboratively at each generation. As the complexity of optimization problems and the cost of solutions increase in practical applications, how to efficiently solve expensive constrained optimization problems with limited computational resources has become an important area of research. Traditional optimization algorithms often struggle to balance the efficiency of global and local searches, especially when dealing with high-dimensional and complex constraint conditions.
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