AI Article Synopsis
- Sarcopenia is a significant condition affecting many older adults, and this study focused on its prevalence and fall risk among Parkinson’s disease (PD) patients in Brazil.
- Out of 218 PD patients evaluated, 55.5% screened positive for sarcopenia, with several factors like disease duration and gender linking to both sarcopenia and fall risks.
- The findings highlight the need for proactive screening and management of sarcopenia in PD patients to improve their quality of life and reduce fall incidents.
Article Abstract
Background: Sarcopenia is a complex and multifactorial geriatric condition seen in several chronic degenerative diseases. This study aimed to screen for sarcopenia and fall risk in a sample of Parkinson's disease (PD) patients and to investigate demographic and clinical factors associated.
Methods: This is a cross-sectional study. We evaluated 218 PD patients at the Movement Disorders Clinic in Fortaleza, Brazil, and collected clinical data including experiencing falls in the six months prior to their medical visit. Probable sarcopenia diagnosis was confirmed by using a sarcopenia screening tool (SARC-F questionnaire) and the presence of low muscle strength.
Results: One hundred and twenty-one patients (55.5%) were screened positive for sarcopenia using the SARC-F and 103 (47.4%) met the criteria for probable sarcopenia. Disease duration, modified Hoehn and Yahr stage, Schwab and England Activities of Daily Living Scale score, levodopa equivalent dose, probable sarcopenia and positive SARC-F screening were all associated with experiencing falls. Disease duration, lower quality of life and female gender were independently associated with sarcopenia. Experiencing falls was significantly more frequent among patients screened positive in the SARC-F compared to those screened negative.
Conclusions: Sarcopenia and PD share common pathways and may affect each other's prognosis and patients' quality of life. Since sarcopenia is associated with lower quality of life and increased risk of falls, active case finding, diagnosis and proper management of sarcopenia in PD patients is essential.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082018 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227238 | PLOS |
Publication Analysis
Top Keywords
Similar Publications
Fractures in sub-Saharan Africa: epidemiology, economic impact and ethnography (Fractures-E ): study protocol.
Wellcome Open Res
June 2023
Musculoskeletal Research Unit, University of Bristol, Bristol, England, BS10 5NB, UK.
The population of older adults is growing in sub-Saharan Africa. Ageing exponentially increases fragility fracture risk. Of all global regions, Africa is projected to observe the greatest increase in fragility fractures.
View Article and Find Full Text PDFApplication of Orofacial Muscle Strength Measurement to Screen for Penetration/Aspiration Risk in Older Adults With Sarcopenia: A Diagnostic Accuracy Study.
J Oral Rehabil
January 2025
Research Institute for Korean Medicine, Pusan National University, Yangsan, Republic of Korea.
Background: Early identification of penetration/aspiration (P/A) risk in older adults with sarcopenia is crucial to prevent complications and maintain quality of life.
Purpose: To evaluate the diagnostic utility of orofacial muscle strength measurements for predicting the risk of P/A in older adults with sarcopenia.
Methods: In this observational and prospective study, we collated consecutive data from community-dwelling older adults diagnosed with sarcopenia at a musculoskeletal disorder clinic.
Accelerated epigenetic ageing after burn injury.
Geroscience
January 2025
Inflammation and Ageing, University of Birmingham, Birmingham, UK.
Individuals who suffer a major burn injury are at higher risk of developing a range of age-associated diseases prematurely leading to an increase in mortality in adult and juvenile burn injury survivors. One possible explanation is that injury is accelerating the biological ageing process. To test this hypothesis, we analysed DNA methylation in peripheral blood mononuclear cells from adult burn-injured patients (> 5%TBSA) upon admission to hospital and 6 months later, to calculate an epigenetic clock value which can be used to determine biological age.
View Article and Find Full Text PDFEvaluation of using grip strength and hand muscle cross-sectional area to predict secondary fractures post distal radius fracture.
Arch Osteoporos
January 2025
Department of Orthopaedics and Traumatology, Queen Mary Hospital The University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong, China.
Unlabelled: Grip strength measurement, as a surrogate of sarcopenia diagnosis, effectively predicts secondary fracture risk in distal radius fracture patients. This simple tool enhances clinical practice by identifying high-risk patients for targeted interventions, potentially preventing or reversing functional decline and recurrent fractures.
Purpose: To evaluate grip strength and hand muscle cross-sectional area as predictors of secondary fracture risk in patients with a history of distal radius fracture (DRF), serving as surrogates of the diagnosis of sarcopenia.
Synergistic effect of sarcopenia and ASA status in predicting mortality after emergency laparotomy: a systematic review and meta-analysis with meta-regression.
Updates Surg
January 2025
Department of General Surgery, Morriston Hospital, Swansea, UK.
The aim of this study was to investigate the relationship between sarcopenia and American Society of Anesthesiologists (ASA) status in predicting post-operative mortality after emergency laparotomy. A PRISMA-compliant systematic review and meta-analysis (using random effects modelling) was performed searching for studies reporting 30-day mortality risk in patients with sarcopenia undergoing emergency laparotomy. The ASA status of sarcopenic and non-sarcopenic patients was determined, and the effect of difference in ASA status on 30-day mortality in sarcopenic and non-sarcopenic patients was determined via a meta-regression model.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!