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Purpose Of Review: The purpose of this review is to provide the most recent update and summary on the consideration, benefits and application of regional anesthesia in the ICU setting, as it pertains to the management of perioperative pain.

Recent Findings: Regional anesthesia and analgesia have become ubiquitous in the perioperative setting, with numerous indications and benefits. As integral part of the multimodal analgesia approach, various regional blocks have been increasingly utilized in critically ill patients.

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Acne vulgaris, caused by pathophysiological processes at the pilosebaceous unit, is among the most common chronic dermatological disorders. Acne sequelae, including scarring and dyspigmentation, are common, and are often more distressing to patients than active acne lesions, reinforcing the importance of prevention and effective treatment. Trifarotene, a novel fourth generation retinoid selective for retinoid acid receptor gamma, is approved for the management of moderate-to-severe facial and truncal acne, with recent data supporting its efficacy in acne-induced hyperpigmentation.

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Objectives: Although physical therapy is recommended as part of the non-pharmacological management of patients with psoriatic arthritis (PsA), the evidence is still unclear. Therefore, this study aimed to systematically review and appraise the quality of research on physical therapy in the management of patients with PsA.

Methods: In June 2024, a systematic literature search using four different databases (Medline, Embase, Web of Science and the Cochrane Library) was performed to include interventional and observational studies examining physical therapy in patients with PsA (PROSPERO ID 255501).

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An Overview on the Management of Atrophic Acne Scars: The Role of Trifarotene as an Adjunct.

Skin Therapy Lett

July 2024

Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada.

Article Synopsis
  • Acne vulgaris is a widespread inflammatory skin condition that affects people of all ages and can lead to lasting effects like scarring and color changes, which significantly impact mental health.
  • Treatment for acne scarring involves various methods including topical creams, physical procedures, and laser therapies, with the best results often seen using a combination of these approaches.
  • Trifarotene is a new type of retinoid approved for moderate-to-severe acne in people over 12, showing promise in treating acne scarring by specifically targeting a common receptor in the skin.
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Purpose: Spinal epidural hematoma (SEH) is a rare yet significant complication associated with neuraxial anesthesia. Here, we present the case of a 74-yr-old male who underwent open repair of an abdominal aortic aneurysm. Following the removal of an epidural catheter, the patient developed anterior spinal cord syndrome due to an SEH despite having a normal coagulation profile.

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