AI Article Synopsis
- - Three new inositol angelates and two new tirucallane-type alkaloids were discovered, with their structures identified using advanced techniques like 1D and 2D NMR and HR-ESI-MS.
- - The compounds showed notable cytotoxic effects against the HepG2 human cancer cell line, with IC values of 8.4 and 13.2 μM, indicating their potential as cancer treatments.
- - Additionally, the compounds demonstrated significant growth inhibition against larvae, suggesting they may have applications in pest control as well.
Article Abstract
Three new inositol angelate compounds () and two new tirucallane-type alkaloids ( and ) were isolated from the , and their structures were established mainly by means of combination of 1D and 2D nuclear magnetic resonance and HR-ESI-MS. Based on cytotoxicity testing, compounds and exhibited significant cytotoxic activity against human cancer cell line HepG2 with IC value at 8.4 and 13.2 μM. In addition, compounds and also showed remarkable growth inhibitory activity to larvae.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179408 | PMC |
| http://dx.doi.org/10.3390/molecules25051222 | DOI Listing |
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