Application of Focal Photoinduced Thrombosis for Modeling Spinal Cord Ischemia.

Bull Exp Biol Med

Department of Histology, Cytology and Embryology, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia.

Published: February 2020

Typical ischemic damage to neurons were detected in the focus of experimental photothrombosis and in the transition zone. They were associated with symptoms of impaired motor functions and dysfunction of pelvic organs. The applied method of focal photothrombosis can be used for simulation of spinal cord ischemia for the development of methods for pharmacological correction and restoration of impaired sensorimotor functions.

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Source
http://dx.doi.org/10.1007/s10517-020-04746-4DOI Listing

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