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Cloud radiative effect dominates variabilities of surface energy budget in the dark Arctic.
Sci Rep
January 2025
Lawrence Livermore National Laboratory, Livermore, CA, USA.
Climate models simulate a wide range of temperatures in the Arctic. Here we investigate one of the main drivers of changes in surface temperature: the net surface heat flux in the models. We show that in the winter months of the dark Arctic, there is a more than two-fold difference in the net surface heat fluxes among the models, and this difference is dominated by the downward infrared radiation from clouds.
View Article and Find Full Text PDFTidal-driven NO emission is a stronger resister than CH to offset annual carbon sequestration in mangrove ecosystems.
Sci Total Environ
January 2025
State Key Laboratory of Marine Resource Utilization in South China Sea, School of Ecology, School of Marine Science and Engineering, Hainan University, Haikou, Hainan, China; Collaborative Innovation Center of Marine Science and Technology, Hainan University, Haikou, Hainan, China. Electronic address:
The mangrove ecosystems store a significant amount of "blue carbon" to mitigate global climate change, but also serve as hotspots for greenhouse gases (GHGs: CO, CH and NO) production. The CH and NO emissions offset mangrove carbon benefits, however, the extent of this effect remains inadequately quantified. By applying the 36 h time-series observations and mapping cruises, here we investigated the spatial and temporal distribution of GHGs and their fluxes in Dongzhaigang (DZG) bay, the largest mangrove ecosystem in China, at tidal and monthly scales.
View Article and Find Full Text PDFInvestigation of the threonine metabolism of Echinococcus multilocularis: The threonine dehydrogenase as a potential drug target in alveolar echinococcosis.
Int J Parasitol Drugs Drug Resist
January 2025
Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland; Multidisciplinary Center for Infectious Diseases, University of Bern, Bern, Switzerland. Electronic address:
Alveolar echinococcosis (AE) is a severe zoonotic disease caused by the metacestode stage of the fox tapeworm Echinococcus multilocularis. We recently showed that E. multilocularis metacestode vesicles scavenge large amounts of L-threonine from the culture medium.
View Article and Find Full Text PDFA whole-body imaging technique for tumor-specific diagnostics and screening of B7-H3-targeted therapies.
J Clin Invest
January 2025
Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing, China.
Background: B7-H3 or CD276 is notably overexpressed in various malignant tumor cells in humans, with extremely high expression rates. The development of a radiotracer that targets B7-H3 may provide a universal tumor-specific imaging agent and allow the noninvasive assessment of the whole-body distribution of B7-H3-expressing lesions.
Methods: We enhanced and optimized the structure of an affibody (ABY) that targets B7-H3 to create the radiolabeled radiotracer [68Ga]Ga-B7H3-BCH, and then, we conducted both foundational experiments and clinical translational studies.
Biological, linguistic, and individual factors govern voice qualitya).
J Acoust Soc Am
January 2025
USC Viterbi School of Engineering, University of Southern California, Los Angeles, California 90089-1455, USA.
Voice quality serves as a rich source of information about speakers, providing listeners with impressions of identity, emotional state, age, sex, reproductive fitness, and other biologically and socially salient characteristics. Understanding how this information is transmitted, accessed, and exploited requires knowledge of the psychoacoustic dimensions along which voices vary, an area that remains largely unexplored. Recent studies of English speakers have shown that two factors related to speaker size and arousal consistently emerge as the most important determinants of quality, regardless of who is speaking.
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