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Malignant ocular teratoid medulloepithelioma in two cats.
J Comp Pathol
February 2023
CytoPath, The Southend, Ledbury, Herefordshire, UK.
Medulloepithelioma is a type of rare primitive neuroectodermal tumour. Most medulloepitheliomas are intraocular and they have been most frequently reported in horses and dogs. A single feline case has been reported but the teratoid form has not been previously reported in cats.
View Article and Find Full Text PDFA Case Report of Chordoma Presenting as a Sphenoid Sinus Mass: A Diagnostic Challenge.
Curr Med Imaging
May 2023
Department of Pathology, All India Institute of Medical Sciences Jodhpur, Rajasthan 342005, India.
Introduction: Chordomas are midline tumors that arise from remnants of the primitive notochord, while the heterotopic rests are usually situated extradural within the bones of the axial skeleton. The tumor is locally aggressive with a high recurrence rate but rarely gives rise to metastasis.
Case Report: A 55-year-old female presented with complaints of headache and intermittent vomiting for six months and diminution of vision for the last four months.
The embryonic node behaves as an instructive stem cell niche for axial elongation.
Proc Natl Acad Sci U S A
February 2022
Department of Cell and Developmental Biology, University College London, WC1E 6BT London, United Kingdom;
In warm-blooded vertebrate embryos (mammals and birds), the axial tissues of the body form from a growth zone at the tail end, Hensen's node, which generates neural, mesodermal, and endodermal structures along the midline. While most cells only pass through this region, the node has been suggested to contain a small population of resident stem cells. However, it is unknown whether the rest of the node constitutes an instructive niche that specifies this self-renewal behavior.
View Article and Find Full Text PDFMouse Models in Meningioma Research: A Systematic Review.
Cancers (Basel)
July 2021
Institut du Cerveau et de la Moelle Épinière, INSERM U1127 CNRS UMR 7225, F-75013 Paris, France.
Meningiomas are the most frequent primitive central nervous system tumors found in adults. Mouse models of cancer have been instrumental in understanding disease mechanisms and establishing preclinical drug testing. Various mouse models of meningioma have been developed over time, evolving in light of new discoveries in our comprehension of meningioma biology and with improvements in genetic engineering techniques.
View Article and Find Full Text PDFEmbryonic evidence uncovers convergent origins of laryngeal echolocation in bats.
Curr Biol
April 2021
Research and Development Center for Precision Medicine, University of Tsukuba, 1-2 Kasuga, Tsukuba-shi, Ibaraki 305-8550, Japan; Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong; Department of Molecular Craniofacial Embryology, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan. Electronic address:
Bats are the second-most speciose group of mammals, comprising 20% of species diversity today. Their global explosion, representing one of the greatest adaptive radiations in mammalian history, is largely attributed to their ability of laryngeal echolocation and powered flight, which enabled them to conquer the night sky, a vast and hitherto unoccupied ecological niche. While there is consensus that powered flight evolved only once in the lineage, whether laryngeal echolocation has a single origin in bats or evolved multiple times independently remains disputed.
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