Nonunion after a proximal fifth metatarsal fracture can cause considerable pain, with high morbidity and loss of work. Although many authors advocate early surgical management of zone 3 injuries (Jones fractures), zone 1 and 2 fractures are generally expected to heal with conservative management. Uncommonly, zone 1 and 2 fractures can develop nonunions. The aim of this study was to evaluate the efficacy of closed intramedullary screw fixation for nonunions of the fifth metatarsal base. We performed a prospective study involving all fifth metatarsal base nonunions treated in our department over 2 years. Only minimally displaced adult fractures were considered for this study. The fracture pattern was categorized using the Dameron classification (zone 1, styloid process; zone 2, metadiaphyseal area; zone 3, proximal diaphysis). All nonunions were fixed percutaneously under radiographic guidance, without fracture site preparation. Zone 1 injuries were fixed using a 3-mm headless compression screw, and those of zones 2 and 3, with an intramedullary 4-mm screw. Of 30 patients included in this study, a minimum 6-month clinical follow-up was obtained. The average time from injury to treatment was 5.9 months (range 3 to 36). There were no smokers in this patient cohort. There were 12 zone 1 injuries, 9 zone 2 injuries, and 9 zone 3 injuries. All patients achieved union by 3 months after screw fixation, with 29 of 30 achieving union by 6 weeks. All patients had resolution of symptoms. There were no complications. We conclude that percutaneous fixation of fifth metatarsal base nonunions, without fracture site preparation, achieves excellent results. We believe that the screw alters the strain of the fracture, thus promoting fibrous-to-osseous conversion and therefore union.
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http://dx.doi.org/10.1053/j.jfas.2019.08.034 | DOI Listing |
Environ Sci Pollut Res Int
January 2025
Slovak Hydrometeorological Institute, Jeséniova 17, Bratislava, 833 15, Slovakia.
This study focused on testing the response of the assimilation apparatus of evergreen Pinaceae species to increasing levels of oxidative stress simulated in manipulative experiments. Needles were collected from mature individuals of Pinus mugo, Pinus cembra, Pinus sylvestris, Abies alba, and Picea abies at the foothill (FH) and alpine treeline ecotone (ATE) in the High Tatras (Western Carpathians). The injury index (INX), quantified by the modified electrolyte leakage (EL) method, indicated severe needle damage due to exposure to extremely high levels of O.
View Article and Find Full Text PDFBMC Genomics
January 2025
College of Forestry and Grassland, Nanjing Forestry University, Nanjing, 210037, China.
Cold stress in winter is one of the most severe abiotic stresses on plant growth and flourishing, and the selection of cold tolerant genotypes is an important strategy to ensure the safety of plant growth and development. Cyclocarya paliurus, a diclinous and versatile tree species originally in subtropical regions, has been introduced and cultivated in the warm temperate zone of China to meet the increasing market demand for its leaf yield. However, information regarding its cold tolerance remains limited.
View Article and Find Full Text PDFBurns
December 2024
Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Clinical Sciences Building, 11, Mandalay Road, 308232, Singapore; Skin Research Institute Singapore, Level 17, Clinical Sciences Building, 11, Mandalay Road, 308232, Singapore; National Skin Centre Singapore, 1 Mandalay Rd, 308205, Singapore. Electronic address:
Burns are dynamic injuries characterized by an initial zone of necrosis that progresses to compromise surrounding tissue. Acute inflammation and cell death are two main factors contributing to burn progression. These processes are modulated by Connexin43 (Cx43) hemichannels and gap junctions in burns and chronic wounds.
View Article and Find Full Text PDFEur J Appl Physiol
January 2025
Department of Medicine, University of Udine, P. le Kolbe 4 - 33100, Udine, Italy.
Purpose: The aim of this study was to investigate the influence of prolonged aerobic exercise on cardiac, muscular and renal inflammatory markers in a group of trained obese men.
Methods: Seventeen men (aged 40 ± 6 years; body mass index [BMI] 31.3 ± 2.
Korean J Ophthalmol
January 2025
Department of Ophthalmology, Gil Medical Center, Incheon, Gachon University College of Medicine, Incheon, Korea.
Purpose: To analyze the frequency, and clinical characteristics of ocular injuries in patients with prior blow-out fractures who experience new blunt trauma, and to assess whether old orbital fractures provide a protective effect against subsequent ocular trauma.
Methods: The medical records of 1,315 ocular trauma patients were reviewed. A total of 927 patients who had orbital or facial CT scans and ophthalmologist evaluations were considered.
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