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Green preparation of low-molecular-weight galactomannan from Gleditsia sinensis and mechanistic investigation on ameliorating nonalcoholic fatty liver disease.
Food Res Int
February 2025
Department of Chemistry and Chemical Engineering, State Key Laboratory of Efficient Production of Forest Resources, Engineering Research Center of Forestry Biomass Materials and Bioenergy (Ministry of Education), Beijing Forestry University, Beijing 100083, China. Electronic address:
Galactomannan comes from a wide range of plant resources and has some biological activities, but its bioavailability is limited due to its large molecular weight and complex structure. In this study, three degradation methods (HO, ultrasound, and β-mannanase) combined with ethanol fractional precipitation (25 %, 50 %, and 75 %) were used to degrade and separate Gleditsia sinensis galactomannans (GSG), and the physicochemical properties and biological activities of GSG after degradation were analyzed. Comprehensive comparison indicates that HO exhibits had a better degradation effect.
View Article and Find Full Text PDFAutophagy activation alleviates annulus fibrosus degeneration via the miR-2355-5p/mTOR pathway.
J Orthop Surg Res
January 2025
Orthopedic Institute, Department of Orthopaedic Surgery, The First Affiliated Hospital, Suzhou Medical College, Soochow University, Suzhou, 215006, Jiangsu, China.
Background: Intervertebral disc degeneration disease (IVDD) is a major cause of disability and reduced work productivity worldwide. Annulus fibrosus degeneration is a key contributor to IVDD, yet its mechanisms remain poorly understood. Autophagy, a vital process for cellular homeostasis, involves the lysosomal degradation of cytoplasmic proteins and organelles.
View Article and Find Full Text PDFAuNPs/GO/Pt microneedle electrochemical sensor for in situ monitoring of hydrogen peroxide in tomato stems in response to wounding stimulation.
Anal Bioanal Chem
January 2025
School of Life Sciences, Nantong University, 9 Seyuan Road, Nantong, 226019, Jiangsu, China.
Hydrogen peroxide (HO) is a critical signaling molecule with significant roles in various physiological processes in plants. Understanding its regulation through in situ monitoring could offer deeper insights into plant responses and stress mechanisms. In this study, we developed a microneedle electrochemical sensor to monitor HO in situ, offering deeper insights into plant stress responses.
View Article and Find Full Text PDF[The effect of concentrated growth factor on the biological performance of human dental pulp stem cells under oxidative stress status].
Zhonghua Kou Qiang Yi Xue Za Zhi
January 2025
Department of Stomatology, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, China.
To investigate the effect of concentrated growth factor (CGF) on the biological performance of human dental pulp stem cells (hDPSCs) under oxidative stress status induced by hydrogen peroxide (HO). The hDPSCs were isolated by using tissue block separation method from healthy permanent teeth extracted for orthodontic reason. hDPSCs surface markers CD34, CD45, CD90 and CD105 were detected by flow cytometry.
View Article and Find Full Text PDFCollaborative performance of enzymatic saccharification and organic pollutant degradation from PHP (phosphoric acid coupled with hydrogen peroxide) pretreatment of lignocellulose.
J Environ Manage
January 2025
College of Environmental Science, Sichuan Agricultural University, Chengdu, Sichuan, 611130, PR China; Sichuan Provincial Engineering Research Center of Agricultural Non-point Source Pollution Control, Sichuan Agricultural University, Chengdu, Sichuan, 611130, PR China.
As a newly developed technology, lignocellulose pretreatment of PHP (phosphoric acid coupled with hydrogen peroxide) can facilitate the enzymatic hydrolysis of pretreated lignocellulose for glucose production. It also has been found that the derived oxidative tail gas from pretreatment can facilely degrade organic pollutant. To balance the pollutant degradation and the glucose yield, the collaborative optimization on pretreatment was investigated.
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