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| http://dx.doi.org/10.1016/S2468-1253(20)30076-5 | DOI Listing |
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Neurobiology of COVID-19-Associated Psychosis/Schizophrenia: Implication of Epidermal Growth Factor Receptor Signaling.
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March 2025
Molecular Psychoneuroimmunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
COVID-19 exhibits not only respiratory symptoms but also neurological/psychiatric symptoms rarely including delirium/psychosis. Pathological studies on COVID-19 provide evidence that the cytokine storm, in particular (epidermal growth factor) EGF receptor (EGFR, ErbB1, Her1) activation, plays a central role in the progression of viral replication and lung fibrosis. Of note, SARS-CoV-2 virus (specifically, S1 spike domain) mimics EGF and directly transactivates EGFR, preceding the inflammatory process.
View Article and Find Full Text PDFResearch review and transcriptomic insights into Benzalkonium chloride inhalation and disease association.
Ecotoxicol Environ Saf
January 2025
College of Pharmacy, Korea University, Sejong 30019, South Korea. Electronic address:
The widespread use of disinfectants, particularly during the coronavirus disease (COVID-19) pandemic, has significantly increased human exposure to biocides, raising concerns about their potential health risks, especially when inhaled. Benzalkonium chloride (BKC), a quaternary ammonium compound commonly used as a disinfectant and preservative, is a notable example because it is frequently used in household products and medical settings. Despite its broad usage, limited research has been conducted on the respiratory and systemic toxicities of BKC.
View Article and Find Full Text PDFQuality of caring interactions between nurses and patients during the COVID-19 pandemic: A cross-sectional survey with nurses and patients in acute and community care.
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Center of Clinical Nursing Science, University Hospital Zurich, Zurich, Switzerland.
Article Synopsis
- The study aimed to analyze the quality of nurse-patient interactions during the early COVID-19 pandemic in both acute and home care settings.
- The research involved a survey with 443 nurses and 295 patients, using the Individualized Care Scale to measure perceptions of care individuality, with nurses rating their own support of patient individuality significantly higher than patients did.
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Extending and Testing Protection Motivation Theory in the Context of COVID-19 Contact-Tracing Technology: A Comparison of South Korea and the United States.
Health Commun
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Department of Communications and New Media, National University of Singapore.
This study applies protection motivation theory (PMT) to the COVID-19 contact-tracing context by including privacy concerns, collective efficacy, and a mediator (fear of COVID-19) and tests it in the US and South Korea. The study uses a structural equation modeling (SEM) approach and a sample of 418 Americans and 444 South Koreans. According to the results, fear was positively associated with adoption intentions in the US sample but not in the Korean sample.
View Article and Find Full Text PDFCOVID-19 Misperceptions and Masking Compliance: A Support Marshaling Analysis.
Health Commun
January 2025
Department of Communication, Banner Alzheimer's Institute.
Misperceptions strongly influence the extent to which individuals comply with preventative measures. Social support from others, particularly given widespread mistrust in news media among those holding misperceptions, plays an important role in shaping compliance with preventative measures. The impact of social support, however, is not straightforward and not all support results in greater compliance.
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