Necrotizing infections are rapidly spreading progressive infections with necrosis of the subcutaneous tissue that can have severe complications. We report a case of right breast necrotizing mastitis in a 40-year-old postpartum woman who presented in septic shock. The patient was resuscitated with intravenous fluids and broad-spectrum antibiotics, followed by urgent surgical debridement. We discuss the patient's presentation, our treatment approach, and outcomes, with a brief review of the literature. We conclude that necrotizing breast infections are rare, but must be known to obstetricians and breast and surgical oncologists, because without urgent treatment and surgical debridement, the mortality risk is high.
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http://dx.doi.org/10.1111/tbj.13799 | DOI Listing |
Alzheimers Dement
December 2024
Seoul National University, Seoul, Seoul, Korea, Republic of (South).
Background: Wandering is a common issue among individuals living with dementia. This behavior often leads to increased worry for family caregivers, as those with dementia are at a heightened risk of becoming lost. Location-tracking devices have potential as effective tools for providing independence to individuals living with dementia while reducing the risk of them getting lost.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Euro-Mediterranean University of Fez (UEMF), Fez, Fez, Morocco.
Background: The spread of fake news may lead to a disparate wave of digital health-seeking behavior, cyberchondria, anxiety, indecision, and other psychosocial dysfunctions, including collapse in social capital and stigmatization. In this study, we utilized a bibliometric analysis to discern the primary trends associated with health communication and health-seeking behavior regarding dementia-related contents in countries within the Middle East and North African (MENA) region.
Method: A literature review was conducted in November 2023.
Alzheimers Dement
December 2024
Universidad Autónoma de San Luis Potosi, San Luis Potosi, SL, Mexico.
Background: Following a diagnosis of dementia, the patient experiences changes that mainly affect his cognitive behavior. Various behavioral therapies are currently being explored to reduce these symptoms and improve the patient's quality of life.
Method: Flow chart RESULT: In the context of the emotional impact associated with the diagnosis of dementia, the search for interventions to mitigate emotional and social deterioration in patients has intensified.
Alzheimers Dement
December 2024
University at Albany, SUNY, Albany, NY, USA.
Background: The experience of spouse caregivers of individuals with Alzheimer's Disease (AD) is marked by witnessing the gradual cognitive decline of their loved ones. This journey transforms the nature of their marital relationship, evolving from mutual interdependence to a more unilateral caregiving role. Despite this significant shift, the specific phenomenon of self-loss among these caregivers remains underexplored in academic research.
View Article and Find Full Text PDFDrug Deliv
December 2025
Biomedical Materials and Devices for Revolutionary Integrative Systems Engineering (BMD-RISE) Research Unit, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand.
Biopolymers, such as collagens, elastin, silk fibroin, spider silk, fibrin, keratin, and resilin have gained significant interest for their potential biomedical applications due to their biocompatibility, biodegradability, and mechanical properties. This review focuses on the design and integration of biomimetic peptides into these biopolymer platforms to control the release of bioactive molecules, thereby enhancing their functionality for drug delivery, tissue engineering, and regenerative medicine. Elastin-like polypeptides (ELPs) and silk fibroin repeats, for example, demonstrate how engineered peptides can mimic natural protein domains to modulate material properties and drug release profiles.
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