AI Article Synopsis
- Accurate analysis of muscle condition in lower limb injuries is crucial, yet traditional microscopic tissue analysis can distort the tissue structure.
- The study utilized synchrotron X-ray imaging to perform detailed three-dimensional analysis of muscle samples taken from mice with induced nerve injuries.
- Findings from this research contribute valuable data for understanding muscle injury and have potential applications in enhancing medical imaging techniques.
Article Abstract
Damage to lower limb muscles requires accurate analysis of the muscular condition via objective microscopic diagnosis. However, microscopic tissue analysis may cause deformation of the tissue structure due to injury induced by external factors during tissue sectioning. To substantiate these muscle injuries, we used synchrotron X-ray imaging technology to project extremely small objects, provide three-dimensional microstructural analysis as extracted samples. In this study, we used mice as experimental animals to create soleus muscle models with various nerve injuries. We morphologically analyzed and quantified the damaged Section and Crush muscles, respectively, via three-dimensional visualization using synchrotron radiation X-ray imaging to diagnose muscle injury. Results of this study can also be used as basic data in the medical imaging field.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067770 | PMC |
| http://dx.doi.org/10.1038/s41598-020-61599-7 | DOI Listing |
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