At 19-week gestation, a 32-year-old Japanese woman presented with a 3-day history of fever and vesicular rashes on the skin and was diagnosed with varicella, which resolved after antiviral therapy. In the primary clinic, her immunity to rubella and measles, but not to varicella, was confirmed at preconception counseling. Maternal varicella infection can cause congenital varicella syndrome characterized by congenital malformations and neurological deficits. This case recommends that all women of childbearing age should be assessed for immunity to varicella before pregnancy and that primary care physicians should take initiatives for preventing maternal varicella.
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| http://dx.doi.org/10.1002/jgf2.291 | DOI Listing |
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Article Synopsis
- * The exact causes of LCH are not well understood, but they may involve genetic factors, immune system issues, and environmental influences during pregnancy.
- * This report discusses a case of a newborn girl with LCH whose mother had a varicella-zoster infection during pregnancy, hinting at a potential link between prenatal factors and the condition.
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