Background: Hyperuricemia is a risk factor for cardiovascular diseases, but the impact of hyperuricemia and sex-related disparities is not fully clear in elderly patients with acute coronary syndrome (ACS).

Objective: To investigate the association between hyperuricemia and 1-year all-cause mortality in elderly patients with ACS.

Methods: This retrospective cohort study included 711 consecutive ACS patients aged ≥75 years, hospitalized in our center between January 2013 and December 2017. Serum uric acid (sUA), in-hospital events, and 1-year follow-up were analyzed. Multivariable logistic regression models were used to explore the risk factors for in-hospital events and 1-year all-cause mortality.

Results: sUA levels were higher in males than in females (381.4 ± 110.1 vs. 349.3 ± 119.1 mol/l, < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, < 0.001). Prevalence of hypertension (80.5% vs. 72.6%, < 0.001). Prevalence of hypertension (80.5% vs. 72.6%.

Conclusions: Hyperuricemia is an independent risk factor for 1-year all-cause mortality in elderly female patients with ACS.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057023PMC
http://dx.doi.org/10.1155/2020/2615147DOI Listing

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