AI Article Synopsis
- A study aimed to investigate the prevalence and impact of eye symptoms in Parkinson's Disease (PD) patients compared to healthy controls using the Visual Impairment in Parkinson's Disease Questionnaire (VIPD-Q).
- In a sample of 848 PD patients and 250 controls, 82% of PD patients reported at least one eye symptom, which was significantly higher than the 48% reported by controls, indicating more severe symptoms across all categories.
- These eye symptoms were shown to disrupt daily activities in 68% of PD patients, emphasizing the need for effective screening tools like the VIPD-Q for better management and treatment of these symptoms.
Article Abstract
Objective: To determine the prevalence and clinical effect of ophthalmologic symptoms in patients with Parkinson disease (PD), compared with controls, using a standardized questionnaire.
Methods: In this observational, cross-sectional, multicenter study, 848 patients with PD and 250 healthy controls completed the Visual Impairment in Parkinson's Disease Questionnaire (VIPD-Q). The VIPD-Q addressed 4 domains according to structures: (1) ocular surface; (2) intraocular; (3) oculomotor; and (4) optic nerve. The questionnaire also assessed the effect of ophthalmologic symptoms on daily activities.
Results: One or more ophthalmologic symptoms were reported by 82% (95% confidence interval [CI], 80-85) of patients, compared with 48% (95% CI, 42-54) of controls ( < 0.001). Patients with PD experienced more ophthalmologic symptoms across all domains than controls ( < 0.001), as reflected by a higher VIPD-Q total score among patients (median 10 [interquartile range (IQR) 13]) than controls (median 2 [IQR 5]; < 0.001). Ophthalmologic symptoms interfered with daily activities in 68% (95% CI, 65-71) of patients, compared with 35% (95% CI, 29-41) of controls ( < 0.001).
Conclusion: Patients with PD have a higher prevalence of ophthalmologic symptoms than controls. Moreover, these frequently interfere with daily activities. A screening questionnaire such as the VIPD-Q may help with identifying ophthalmologic symptoms in PD, thereby enabling more timely treatment.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251522 | PMC |
| http://dx.doi.org/10.1212/WNL.0000000000009214 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!