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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061630PMC
http://dx.doi.org/10.1016/j.jpra.2017.05.012DOI Listing

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: Combining autologous fat grafting with implant placement is meant to improve the quality of implant-based breast reconstruction. The present study explores the concept of multi-stage composite breast reconstruction with repeated sessions of autologous fat grafting to increase mastectomy flap thickness and provide better pre-pectoral implant coverage. : Twenty-five consecutive patients underwent bilateral multi-stage composite expander-to-implant breast reconstruction and reverse expansion from August 2020 to April 2024.

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Background Pre-pectoral implant-based breast reconstruction has become increasingly popular because it is associated with less postoperative pain and earlier recovery than traditional sub-pectoral techniques. Acellular dermal matrix (ADM) in pre-pectoral reconstruction is thought to provide additional support for the implant and improve cosmetic outcomes. However, it leads to additional costs.

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Capsular contracture (CC) is a concerning issue for individuals undergoing postmastectomy radiation therapy (PMRT) with implant-based breast reconstruction. This study investigated whether the extent of CC and implant migration differs based on implant placement and the reconstruction stage. Insertion plane and stage of breast implants were investigated, and the presence and severe cases of CC and implant migration were analyzed.

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Article Synopsis
  • The use of acellular dermal matrices (ADMs) like DermaCell in pre-pectoral breast reconstruction has shown benefits but comes with a noted increase in postoperative complications.
  • A study evaluating 230 patients undergoing direct-to-implant breast reconstruction with DermaCell reported a 22.4% overall complication rate, with specific issues like rippling, skin ischemia, and capsular contraction.
  • Despite the complications, patient satisfaction scores increased significantly, indicating that ADM can enhance the overall outcomes of breast reconstructive surgery.
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Background: The aim of the paper is to present a single-center experience with two-stage pre-pectoral breast reconstruction using tissue expander entirely covered by acellular dermal matrix (ADM), reporting surgical indications, technique, clinical and histological outcomes.

Materials And Methods: A prospectively maintained database of consecutive patients who had undergone immediate pre-pectoral expander-based breast reconstruction with ADM over a two years period (2019-2021) was analyzed. The primary clinical outcome measures included patients' subjective assessment of satisfaction and pain.

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