We present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016193PMC
http://dx.doi.org/10.1021/jacs.0c01670DOI Listing

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