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We present the in vitro growth characteristics and morphology of the first established long-term culture of human normal bladder epithelium. Normal bladder cells were grown with a mean generation time of 44 h and a life span of 33 population doublings in 12 weeks. The cells exhibited contact inhibition of growth. The cultures were morphologically examined and compared with transitional cell carcinoma in culture.
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| http://dx.doi.org/10.1159/000473448 | DOI Listing |
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