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Successful Treatment of Risperidone-Induced Hypothermia With Aripiprazole: A Brief Case Report and a Literature Review.
Cureus
August 2024
Department of Psychiatry, MedStar Washington Hospital Center, Washington, DC, USA.
Article Synopsis
- Hypothermia can be a serious condition caused by various factors, including the use of certain medications like antipsychotics, which may lead to decreased body temperature 7-10 days after dosage changes.
- A case study involves a 68-year-old man with multiple health issues, who showed persistent hypothermia even after external warming efforts but improved after switching from risperidone to aripiprazole.
- It's important for healthcare providers to monitor patients on antipsychotics for hypothermia symptoms and check their vital signs regularly for early identification and treatment.
Characteristics of indoor and outdoor fatal hypothermia cases in Chiba, Japan.
Leg Med (Tokyo)
November 2024
Department of Legal Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan; Department of Forensic Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
In forensic medicine, hypothermia is a frequently encountered cause of death, and this characteristic provides public health information to prevent similar deaths in the future. Previous studies revealed regional differences in hypothermia occurrence (indoors or outdoors). However, to our knowledge, no recent studies in Japan have directly compared the characteristics of indoor- and outdoor-onset cases based on forensic autopsy reports.
View Article and Find Full Text PDFThe impact of piperazine and antipsychotic co-exposures and CB1 blockade on the effects elicited by AMB-FUBINACA, a synthetic cannabinoid, in mice.
Eur J Pharmacol
September 2024
Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand. Electronic address:
Article Synopsis
- The study explores the dangers of the synthetic cannabinoid AMB-FUBINACA, which is linked to severe health risks and fatalities, especially when combined with other drugs like pFPP and risperidone.
- Experiments on mice showed that AMB-FUB leads to harmful effects like hypothermia and convulsions, with the combination of AMB-FUB and pFPP worsening these effects; however, risperidone mitigated the convulsions in female mice.
- Understanding the mechanisms behind AMB-FUB toxicity is crucial for developing effective treatments for overdoses and protecting at-risk groups who abuse synthetic cannabinoids.
Antidepressant-like effects of Cimicifuga dahurica (Turcz.) Maxim. via modulation of monoamine regulatory pathways.
Physiol Behav
October 2024
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016, Liaoning, China.
Sheng-ma is recorded in the Compendium of Materia Medica and mainly originates from the rhizomes of Cimicifuga dahurica (Turcz.) Maxim. (CD), Cimicifuga heracleifolia Kom.
View Article and Find Full Text PDFInfluence of fentanyl, medetomidine-fentanyl or acepromazine-fentanyl premedication on oesophageal and rectal temperature in dogs under anaesthesia.
Vet Anaesth Analg
June 2024
Department of Surgery and Orthopaedics, Small Animal Clinic, Faculty of Veterinary Medicine, University of Veterinary Sciences, Brno, Czech Republic.
Objective: To compare changes in oesophageal (T-Oeso) and rectal (T-Rec) temperature in dogs during general anaesthesia and premedicated with fentanyl, medetomidine-fentanyl or acepromazine-fentanyl.
Study Design: Prospective, randomized, blind clinical study.
Animals: A total of 120 healthy dogs, aged 2-10 years and weighing 5-20 kg.
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