This study was designed to test the effect of an increasing- (UP) or decreasing-intensity (DOWN) resistance-training (RT) protocol on the pleasure and enjoyment of RT. The participants (N = 40; mean age = 35.0 ± 9.2 years) completed two RT sessions comprising 3 × 10 repetitions of six exercises. In the UP condition, load progressively increased from 55% to 75% of 1-repetition maximum, while in the DOWN condition, this pattern was reversed (i.e., 75-55% 1-repetition maximum). The DOWN condition resulted in more overall pleasure compared with UP and a slope of increasing pleasure, while the UP condition resulted in decreasing pleasure. Enjoyment of RT, postexercise pleasure, and remembered pleasure were all significantly greater for DOWN compared with UP (all ps > .01). These findings suggest that decreasing RT intensity throughout an exercise bout can elicit a positive slope of pleasure and enhance affective evaluations of exercise.
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http://dx.doi.org/10.1123/jsep.2019-0089 | DOI Listing |
Biol Lett
January 2025
Department of Animal and Veterinary Sciences, Aarhus University, Tjele, Denmark.
The concept of animal welfare is evolving due to progress in our scientific understanding of animal biology and changing societal expectations. Animal welfare science has been primarily concerned with minimizing suffering, but there is growing interest in also promoting positive experiences, grouped under the term positive animal welfare (PAW). However, there are discrepancies in the use of the term PAW.
View Article and Find Full Text PDFJAMA Neurol
January 2025
Department of Neurology and Weill Institute of Neuroscience, University of California, San Francisco.
Elife
January 2025
Department of Neurology, Weill Institute for Neuroscience, University of California San Francisco, San Francisco, United States.
Mutations in Sonic Hedgehog (SHH) signaling pathway genes, for example, (SUFU), drive granule neuron precursors (GNP) to form medulloblastomas (MB). However, how different molecular lesions in the Shh pathway drive transformation is frequently unclear, and mutations in the cerebellum seem distinct. In this study, we show that fibroblast growth factor 5 (FGF5) signaling is integral for many infantile MB cases and that expression is uniquely upregulated in infantile MB tumors.
View Article and Find Full Text PDFCureus
December 2024
Obstetrics and Gynecology, Wright State University Boonshoft School of Medicine, Dayton, USA.
Ben Wa balls are often used for sexual pleasure and pelvic floor exercise. However, their use can lead to complications, including retention within the vagina. We present a case of a 64-year-old female, status post-hysterectomy 20 years prior, who experienced the loss of a Ben Wa ball during sexual activity.
View Article and Find Full Text PDFAlpha Psychiatry
November 2024
Old Age Psychiatry, Lancashire & South Cumbria NHS Foundation Trust, Preston, United Kingdom.
Addiction comes in various forms and can be related to substances like cocaine, opioids, alcohol, cannabis, amphetamine, and nicotine, as well as behaviors like gambling or sex addiction. The impact of addiction places increased economic and medical burdens on society. Currently, the management of addiction is more focused on symptomatic relief rather than targeting the reinforcing mechanisms of dependence on addictive substances and behaviors.
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