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| http://dx.doi.org/10.1161/CIRCULATIONAHA.119.043625 | DOI Listing |
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Whey Protein-Based Hydrogel Microspheres for Endovascular Embolization.
ACS Appl Bio Mater
January 2025
Department of Radiology, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Transarterial embolization (TAE) is an image-guided, minimally invasive procedure for treating various clinical conditions by delivering embolic agents to occlude diseased arteries. Conventional embolic agents focus on vessel occlusion but can cause unintended long-term inflammation and ischemia in healthy tissues. Next-generation embolic agents must exhibit biocompatibility, biodegradability, and effective drug delivery, yet some degradable microspheres degrade too quickly, leading to the potential migration of fragments into distal blood vessels causing off-target embolization.
View Article and Find Full Text PDFSurgical Obliteration of a Filum Terminale Arteriovenous Fistula Following Aborted Endovascular Embolization: Illustrative Case Report and Literature Review.
Cureus
December 2024
Department of Neurological Surgery, Rutgers University New Jersey Medical School, Newark, USA.
Arteriovenous fistulas of the filum terminale are rare vascular malformations that predominantly affect males and can present with various neurological symptoms. In this study, we indexed previously published cases of filum terminale arteriovenous fistulas demonstrating that endovascular and microsurgical management are both proven to be appropriate and successful treatment modalities with low complication rates. Endovascular treatment is far less invasive; however, it is associated with higher failure rates, which need to be managed surgically.
View Article and Find Full Text PDFImpact of thrombus composition on virtual thrombectomy procedures using human clot analogues mechanical data.
J Mech Behav Biomed Mater
January 2025
Department of Chemistry, Materials and Chemical Engineering 'Giulio Natta', Politecnico di Milano, Italy.
Endovascular thrombectomy (EVT) aims at restoring blood flow in case of acute ischemic stroke by removing the thrombus occluding a large cerebral artery. During the procedure with stent-retriever, the thrombus is captured within the device, which is then retrieved, subjecting the thrombus to several forces, potentially leading to its fragmentation. In silico studies, along with mechanical characterisation of thrombi, can enhance our understanding of the EVT, helping the development of new devices and interventional strategies.
View Article and Find Full Text PDFAspiration thrombectomy of the hepatic veins in Budd Chiari Syndrome.
Acta Gastroenterol Belg
January 2025
Department of Radiology, Antwerp University Hospital, Antwerp, Belgium.
Article Synopsis
- Budd-Chiari syndrome (BCS) is a rare, serious condition caused by blocked blood flow from the liver due to clotting.
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Practice-pattern variation in anticoagulation intensity in acute cerebral venous thrombosis: A two-center experience.
J Clin Neurosci
December 2024
Yale New Haven Hospital, Department of Pharmacy, New Haven, CT, United States; Sturdy Health, Population Health, Plainville, MA, United States. Electronic address:
Background And Purpose: Cerebral venous thrombosis (CVT) requires acute anticoagulation. Heparin is commonly used but specific recommendations on intensity and timing are lacking. We sought to characterize practice-pattern variation in the use of unfractionated heparin (UFH) for acute CVT treatment across multiple centers.
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