AI Article Synopsis
- The next-generation sequencing (NGS) market has experienced significant growth, with the global clinical NGS services market projected to rise from $2.2 billion in 2015 to $7.7 billion by 2020.
- The reproductive health NGS tests dominate the market, followed by oncology tests, with the highest demand for tests that sequence more than 50 genes.
- Countries outside the US are also seeing rapid growth in NGS markets, but there are challenges that need to be addressed to ensure sustainable future expansion.
Article Abstract
The market for next-generation sequencing technologies (NGS) has grown dramatically. Health care decision-makers need empirical evidence on market growth and future trends in order to develop appropriate strategies and policies, but little has been published about the nature and size of these trends. We provide a snapshot of market trends through 2020. We found rapid growth of clinical NGS - the global clinical NGS services market was $2.2 billion in 2015 and is forecast to reach $7.7 billion by 2020. The reproductive health NGS test market is the largest market followed by the oncology NGS test market. The largest market is for tests that sequence >50 genes but not the entire exome or genome. Markets are growing rapidly in countries outside of the US. Despite rapid NGS test growth, there are a number of key issues that will need to be addressed to facilitate appropriate future growth.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059995 | PMC |
Publication Analysis
Top Keywords
Similar Publications
Assessment of the safety and gut microbiota modulation ability of an infant formula containing Bifidobacterium animalis ssp. lactis CP-9 or Lactobacillus salivarius AP-32 and the effects of the formula on infant growth outcomes: insights from a four-month clinical study in infants under two months old.
BMC Pediatr
December 2024
Research Product Department, R&D Center, Glac Biotech Co., Ltd, Tainan City, Taiwan.
Background: Breast milk is a natural treasure for infants, and its microbiota contains a rich array of bacterial species. When breastfeeding is not possible, infant formula with probiotics can be used as a sole source or as a breast milk supplement. The main aim of this study was to evaluate the growth outcomes and tolerance of infants consuming an infant formula containing Bifidobacterium animalis ssp.
View Article and Find Full Text PDFDevelopment of a web-based high-throughput marker design program: CAPS (cleaved amplified polymorphic sequence) Maker.
Plant Methods
December 2024
Department of Molecular Genetics, Dong-A University, Saha-gu Nakdong-Daero 550 beongil 37, Busan, 49315, Republic of Korea.
Background: Genetic markers are crucial for breeding crops with desired agronomic traits, and their development can be expedited using next-generation sequencing (NGS) and bioinformatics tools. Numerous tools have been developed to design molecular markers, enhancing the convenience, accuracy, and efficiency of molecular breeding. However, these tools primarily focus on genetic variants within short user-input sequences, despite the availability of extensive omics data for genomic variants.
View Article and Find Full Text PDFOptimizing sequence data analysis using convolution neural network for the prediction of CNV bait positions.
BMC Bioinformatics
December 2024
Albert Szent-Györgyi Health Centre, University of Szeged, Korányi fasor 14-15, Szeged, H-6725, Csongrád-Csanád, Hungary.
Background: Accurate prediction of copy number variations (CNVs) from targeted capture next-generation sequencing (NGS) data relies on effective normalization of read coverage profiles. The normalization process is particularly challenging due to hidden systemic biases such as GC bias, which can significantly affect the sensitivity and specificity of CNV detection. In many cases, the kit manifests provide only the genome coordinates of the targeted regions, and the exact bait design of the oligo capture baits is not available.
View Article and Find Full Text PDFNext-generation Sequencing Improves The Detection of Malignant Biliary Strictures and Changes Management.
Gastrointest Endosc
December 2024
Division of Digestive and Liver Diseases, University of Texas Southwestern, Dallas, TX. Electronic address:
Background And Aims: Malignant biliary strictures (MBS) pose diagnostic and therapeutic challenges due to the frequent indeterminate results after initial sampling. Next generation sequencing (NGS) panel (BiliSeq) offers promise in MBS detection, but real-world performance remains uncertain. This study aimed to assess standard sampling techniques alone and with BiliSeq for malignancy detection in biliary strictures, and to evaluate management changes based on NGS.
View Article and Find Full Text PDFFamily relations of Moche elite burials on the North Coast of Peru (~500 CE): Analyses of the Señora de Cao and relatives.
Proc Natl Acad Sci U S A
January 2025
UCSC Paleogenomics, Department of Anthropology, University of California, Santa Cruz, CA 95064.
The Moche archaeological culture flourished along Peru's North Coast between the 4th and 10th centuries CE and was characterized by a complex social hierarchy dominated by political and religious elites. Previous archaeological evidence suggests kinship was a key factor in maintaining political authority within Moche society. To test this hypothesis, we applied archaeological, genetic, and isotopic methods to examine familial relationships between six individuals, including the prominent Señora de Cao (), buried together in a pyramid-like, painted temple, Huaca Cao Viejo, in the Chicama Valley, Peru.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!