Background: Magnetic resonance imaging (MRI) is useful for evaluating the stability of an osteochondral lesion of the talus (OLT). A T2 high-signal line between the fragment and its bed on MRI is known as a reliable indicator of an unstable lesion. However, the lesion exhibits various conditions even if a T2 high-signal line is observed. The purpose of this study was to evaluate the relationship between the T2 value of a high-signal line and the condition of the area between the fragment and its bed in OLT.
Methods: T2 values of the T2 high-signal line and those of joint fluid were measured from preoperative MRI images in 46 ankles with OLT and the T2 ratio (high-signal line / joint fluid) was calculated. The relationship between the T2 ratio and CT, arthroscopic, and histologic findings was examined.
Results: The mean T2 ratio was 0.48. T2 ratios of cystic lesions (0.62) or bone absorption (0.67) in the bed were significantly higher than those without a cyst (0.40) or no absorption (0.40). The T2 ratio of an unstable lesion (0.51) was significantly lower than that of a stable lesion (0.29). In histologic findings, there were 2 separate patterns: chondral and subchondral bone separations. The T2 ratio of the chondral separation (0.60) was significantly higher than that of bone separation (0.48).
Conclusion: This study showed that the T2 ratio on a high-signal line was a predictor of stability, cyst, and bone absorption in OLT.
Level Of Evidence: Level III, comparative series.
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http://dx.doi.org/10.1177/1071100720910381 | DOI Listing |
Photoacoustics
February 2025
College of Engineering, Department of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen 518055, China.
A novel balloon-type photoacoustic cell (BTPAC) is proposed to facilitate the detection limitations of acetylene (CH) gas achieving ppb level. Here, an ellipsoidal photoacoustic cavity is employed as the platform for gas-light interaction. By strategically directing the excitation source towards the focal point of the ellipsoidal cavity, ensuring its trajectory traverses the focal point upon each reflection from the interior walls.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Neurology, Dalian Municipal Central Hospital of Dalian University of Technology, Dalian, 116033, Liaoning, China.
Talanta
January 2025
School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, 225002, China. Electronic address:
The rapid, sensitive and reliable detection of oral cancer overexpressed 1 (ORAOV 1) is crucial for the early, non-invasive diagnosis of oral squamous cell carcinoma (OSCC). Herein, we are the first to construct an ultrasensitive electrochemical (EC) biosensor based on an entropy-driven "two-way signal output" (TWSO) cyclic circuit for salivary ORAOV 1 detection. This innovative TWSO cyclic circuit can skillfully convert by-products into desired signal-generating units, not only reducing the excessive accumulation of by-products but also improving the utilization efficiency of output chains, thereby achieving rapid reaction kinetics and high signal outputs.
View Article and Find Full Text PDFFront Pharmacol
December 2024
Department of Clinical Psychology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Background: Deutetrabenazine is a widely used drug for the treatment of tardive dyskinesia (TD), and post-marketing testing is important. There is a lack of real-world, large-sample safety studies of deutetrabenazine. In this study, a pharmacovigilance analysis of deutetrabenazine was performed based on the FDA Adverse Event Reporting System (FAERS) database to evaluate its relevant safety signals for clinical reference.
View Article and Find Full Text PDFFront Pediatr
December 2024
Department of Medical Imaging, Second Hospital of Hebei Medical University, Shijiazhuang, China.
Background: Fetal midgut volvulus is a rare disease, with a high risk of potentially life-threatening fetal complications.
Purpose: The aim of this study was to retrospectively analyze the imaging findings of fetal midgut volvulus diagnosed by magnetic resonance imaging (MRI) and explore its value in non-invasive prenatal diagnosis.
Methods: A retrospective collection of data from 156 fetuses suspected of intestinal obstruction by ultrasound examination in our hospital was conducted.
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