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Refining rodent models of spinal cord injury. | LitMetric

Refining rodent models of spinal cord injury.

Exp Neurol

Centre for Neuroscience, Surgery and Trauma, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark St, London E1 2AT, UK. Electronic address:

Published: June 2020

AI Article Synopsis

Article Abstract

This report was produced by an Expert Working Group (EWG) consisting of UK-based researchers, veterinarians and regulators of animal experiments with specialist knowledge of the use of animal models of spinal cord injury (SCI). It aims to facilitate the implementation of the Three Rs (Replacement, Reduction and Refinement), with an emphasis on refinement. Specific animal welfare issues were identified and discussed, and practical measures proposed, with the aim of reducing animal use and suffering, reducing experimental variability, and increasing translatability within this critically important research field.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.expneurol.2020.113273DOI Listing

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