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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522679PMC
http://dx.doi.org/10.1111/all.14259DOI Listing

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The aim of this study was to investigate the enhancement of all-trans retinoic acid (ATRA) loading in nano-lipid emulsions and stability by using oleic acid. The effect of formulation factors including initial ATRA concentration and the type of oil on the physicochemical properties, that is, percentage yield, percentage drug release, and photostability of formulations, was determined. The solubility of ATRA was increased in the order of oleic acid > MCT > soybean oil > water.

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